Job No.: 588000
Location: Parkville campus
Employment Type: Full-time
Duration: 12 month fixed-term appointment
Remuneration: $114,510 – $121,546 pa HEW Level 09 (plus 9.5% employer superannuation)
- - Leading international university – ranked globally in the top 1%
- - Internationally recognised Research Centre
- - Parkville Campus
If you’re after a brilliant career, Monash University can help make it happen. With leading academics and world-class resources, combined with a ranking in the top 100 universities worldwide, we offer all you need to build a brighter future.
Monash Institute of Pharmaceutical Sciences has a welcoming, inclusive and collaborative culture along with countless opportunities for personal and professional development. While this is a fixed term appointment, we have a history of contract renewals for the right person.
The Centre for Drug Candidate Optimisation (CDCO) is an internationally recognised collaborative research centre based within the Monash Institute of Pharmaceutical Sciences (MIPS). It provides expertise in absorption, distribution, metabolism and excretion (ADME) and pharmacokinetics to support lead candidate optimisation and drug discovery programs. Drug candidate optimisation fills a crucial gap between discovery and development by integrating medicinal chemistry and biology with the pharmaceutical sciences to provide a rational means of identifying drug candidates suitable for progression into preclinical and clinical development.
The CDCO currently comprises 23 staff and collaborates with numerous drug discovery groups within academic, commercial and not-for-profit organisations, both nationally and internationally. As the successful applicant, you will join a dedicated and vibrant team of biopharmaceutical scientists to enhance the quality and development potential of new drug discovery candidates. For more information, visit https://platforms.monash.edu/cdco.
Applications are sought for an experienced candidate for the position of Senior Research Manager to lead and manage the drug metabolism and metabolite identification activities within the CDCO. This is a lab-based leadership role, with primary responsibilities for leading a team of 3-4 staff members to study and elucidate mechanisms and biotransformation pathways of drug substances.
We are seeking a candidate with specialist knowledge and experience in applying LC-MS and LC-MS/MS bioanalytical techniques to study drug metabolism.
The candidate will have a relevant postgraduate qualification with a background in bioanalytical/pharmaceutical chemistry, medicinal chemistry or biochemistry and at least five years’ experience relevant to the position or an equivalent combination or relevant experience and/or education/training (A PhD qualification will be highly regarded).
Essential requirements include in-depth knowledge and practical experience in high resolution accurate mass spectrometry, including competence to handle small molecule drug candidates, excellent knowledge of sample preparation procedures for biological samples, significant experience in chromatographic method development, and technical skills to operate and perform regular routine maintenance of associated LC/MS instrumentation. The candidate should also have expert knowledge and significant technical experience in studying mechanisms of hepatic biotransformation, structural identification of metabolites including the identification of reactive metabolites, elucidation of metabolite kinetics and reaction phenotyping. Experience working within a similar field in the pharmaceutical industry is highly desirable.
If you have the background and desire to undertake this role, we welcome your application.
This role is a full-time position; however, flexible working arrangements may be negotiated.
Please note: To address the key selection criteria within your application you must submit a cover letter describing in detail:
- 1. your scientific and technical background, expertise and experience; and
- 2. your leadership and management skills and experience, covering the specific aspects described in the Key Selection Criteria section of the Position Description
For further information please refer to “”https://www.monash.edu/jobs/how-to-apply/applying-for-the-job">How to apply for Monash Jobs".
Prof Susan Charman, Pharmaceuticals, Susan.Charman@monash.edu, +61 3 9903 9626
Tuesday 19 March 2019, 11:55 pm AEDT