Postdoctoral position: RNA Modifications, Hematopoiesis and Cancer

Postdoctoral position: RNA Modifications, Hematopoiesis and Cancer

Lund University (LU)

Lund, Sweden

Job Description
An exciting opportunity for a Postdoctoral Fellow is available within the RNA and Stem Cell Biology group of Dr. Cristian Bellodi at the Division of Molecular Hematology of the Lund Stem Cell Center, Lund University, Sweden.

Our laboratory focuses new post-transcriptional facets of gene expression control in stem and cancer cell at a molecular, cellular and organismal level. We recently uncovered a critical role of RNA modifications in governing protein synthesis and stem cell function (Guzzi et al., Cell 2018). Building from these findings, we have initiated new research lines to study the function of RNA modifying enzymes within different stem cell systems in vivo and several exciting projects are available. Specifically, we are interested in the molecular basis by which RNA modifications regulate normal and malignant hematopoiesis. The applicant will have access to unique genetic models and a wide array of state-of-the-art high-throughput approaches available in our laboratory including genome-wide and single-cell based sequencing methods. Successful candidate should be interested in the clinical application of basic science research toward understanding the mechanisms underlying hematological diseases associated with stem cell dysfunction.

Specific aims
o Develop specific research project(s) under guidance from Group Leader
o Contribute to the production of research papers for publication
o Present findings at regular group meetings and internal seminars
o Divulgate research findings at international meetings
o Improve established models, protocols and/or develops new methods
o Foster collaborations within the team and other members at the Center
o Guide and share knowledge with junior group members
o Acquire academic independence

About us
Our team consists of a highly interactive group of internationally recruited postdocs, PhD students and technicians that are interested in post-transcriptional gene regulation in stem and cancer cells. We are members of the Division of Molecular Hematology composed of 12 research groups with a common focus on hematopoiesis and stem cell research. Our lab is embedded within the Lund Stem Cell Center, an internationally ranked research center within the strategic areas of Stem Cell Biology and Regenerative Medicine, which is part of Lund University, Scandinavia’s largest institution for education and research.

Essential Skills and Requirements
We are looking for highly talented and motivated candidates with a recent PhD (less than 3 years) and proof of productive research. Applicants are expected to work independently as well as part of a research team. A strong background in murine genetics, immunology and RNA biology is highly preferred. Excellent verbal and written English communication skills are required.

To Apply
Applications including (1) cover letter, (2) curriculum vitae, and (3) contact information of three professional references should be emailed to: cristian.bellodi@med.lu.se.

For more information visit:
https://www.med.lu.se/molecular_hematology/investigator_profiles/cristian_bellodi

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Postdoctoral position: RNA Modifications, Hematopoiesis and Cancer