A postdoctoral position is available to investigate cytokine receptor signaling in replication stress and DNA repair. Dr. Tong’s laboratory studies cytokine receptor and ubiquitin signaling in hematopoietic stem cells, bone marrow failure, and leukemia. Hematopoietic stem cells give rise to all circulating blood cells throughout life. Maintenance of stem cell self-renewal, proliferation and differentiation is regulated by complex signaling pathways. Aberrant regulation leads to leukemia. Genome integrity plays a critical role in the prevention of leukemia, ageing, and blood development. This postdoctoral fellow position will focus on studying the mechanisms that safeguard the genome during DNA replication and investigating how failures in these processes impact hematopoietic stem cell function that leads to bone marrow failure and/or leukemia. You can find our recent publication in below website.
Candidates should have a Ph.D. or equivalent degree and experience with investigating biochemistry, cell biology, molecular biology, as well as mouse models.
Highly motivated candidates with publication records are encouraged to apply. Please email or send applications with a brief statement of research experience and interest, CV, and contact information for at least two references to:
Wei Tong, Ph.D
Associate Professor of Pediatrics,
Children’s Hospital of Philadelphia,
University of Pennsylvania School of Medicine,
Co-Director, Hematopoietic Stem Cell program,
Institute for Regenerative Medicine at UPENN
Abramson Bldg. 310D,
3615 Civic Center Blvd.,
Philadelphia, PA 19104