Research Assistant / Associate (drug discovery)

Research Assistant / Associate (drug discovery)

Wren Therapeutics Limited

Cambridge, United Kingdom

Job title: Research Assistant / Associate (drug discovery)

Location: Central Cambridge

Salary range: Competitive salary. Eligible for company-wide discretionary annual bonus plan.

Job summary: Wren Therapeutics Limited is seeking to appoint a talented research assistant or associate for its rapidly growing research division. The appointee will assist in running a busy experimental laboratory and will have specific responsibility, amongst other duties, for the daily running of the C. elegans section of the laboratory. The appointee will also conduct drug discovery research projects, together with other members of the team, and will contribute to the development and application of new methodologies.

• Assist in running a busy experimental laboratory, including maintaining C. elegans strains, designing experiments, and carrying out molecular, biochemical and behavioural assays.
• Write or contribute to publications or disseminate research findings using other appropriate media, including making presentations at conferences or exhibiting work at academic or industry conferences.
• Communicate complex ideas and concepts to those with limited knowledge and understanding as well as to peers. The appointee will also be expected to mentor and coach colleagues with less experience.
• Mentor and coach colleagues with less experience

Skills, qualifications and experience needed:
• Undergraduate degree in biology, biotechnology or a related discipline, at a leading academic institution.
• Specific research expertise in the topic of protein misfolding and aggregation, preferably including in relation to drug discovery and human disease.
• Experience working experimentally with amyloid forming proteins in living organisms.
• Experience in maintaining the daily running of a C. elegans laboratory, and more generally in assisting to run a busy biological, biochemical or molecular biology laboratory (i.e. purchasing, maintenance of equipment).
• Experience in the acquisition and stock maintenance of various C. elegans strains, preparation of bacterial food sources, plates and media along with culturing and synchronising worms for small molecule screening assays.
• Previous experience in handling living cells or organisms would be beneficial.
• Previous experience in microscopy or imaging would be beneficial.
• Fluency in English.

Closing date for applications: Applications must be received by 31st March 2019

Application procedure: Please send a cover letter and CV to

About Wren Therapeutics (Wren): Wren ( is a spin-off company from the University of Cambridge (UK) and Lund University (Sweden), focused on drug discovery and development for protein misfolding diseases. Wren is advancing an entirely novel approach to address this class of diseases, based on more than a decade of research from its scientific founders focused on the chemical kinetics of the protein misfolding process. These advances make it possible to map, and selectively modulate, the complex and non-linear chemical kinetic networks associated with misfolding proteins and disease. Wren’s predictive, quantitative platform is built on concepts from the physical sciences and is a fundamental shift from the descriptive, qualitative methods of traditional biology, which have failed to successfully address these complex systems. Wren is using its unique approach to develop a broad pipeline of small molecule and antibody therapeutics, as well as diagnostics, spanning neurology, ophthalmology and metabolic diseases.


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Research Assistant / Associate (drug discovery)