A postdoctoral research associate position is immediately
available in the laboratory of Dr. Fedulov to study epigenetic mechanisms of
immune regulation, with a specific emphasis on the effects of DNA methylation
on gene transcription.
The laboratory is located in the Division of Surgical
Research, Department of Surgery, Rhode Island Hospital in Providence, RI. The
academic appointment will be through The Division of Biology and Medicine of
Brown University which is composed of the Warren Alpert Medical School and the Program in Biology. The successful candidate can
expect competitive salary and a typical package of benefits and should commit
to 1 -2 years.
The prospective candidate will lead the project on targeted
epigenetic manipulation of gene function by designing and testing gene-specific
DNA demethylase proteins. This is a novel cutting-edge methodology with a
potential for discovery in innovative therapeutics. Other studies in the
laboratory include immune and epigenetic mechanisms of airway disease:
inflammation, asthma and fibrosis.
The potential candidate will have a PhD degree in molecular
biology, epigenetics, immunology or a relevant discipline. A perfect candidate
will have prior experience with molecular biology and epigenetics, flow
cytometry, tissue culture, transduction and related techniques, as well as in
models of lung disease. Specific desired skills include design and testing of
CRISPR-like constructs, overexpression and purification of proteins, PCR and
pyrosequencing. The position requires the ability to work independently.
Excellent communication skills are a must. The candidate should be eligible for
employment in the US.
For consideration, please send your CV, a statement of
research interests and contact information for three referees to email@example.com.