Research Scientist, Viral Immunology
Seeking a highly motivated, creative and collaborative individual with a strong passion for and dedication to discovery of new life-saving medicines. The candidate will join our internal efforts focused on the research and development of novel HIV cure therapeutics, including small molecule drugs, biologics and vaccines. The successful candidate will work in a highly collaborative environment to identify, characterize and optimize vaccine immunogens for research and clinical development. Primary responsibilities will include: designing and optimizing immunogens, performing and validating cell-based immunology assays for mice, human and non-human primate studies, evaluating new targets and therapeutic approaches in a fast-paced team environment. The successful candidate will play a leading role in establishing new vaccine/biotherapeutics discovery capabilities and support lead optimization efforts for HIV cure related projects. In addition the successful candidate would be expected to:
• Design and develop HIV/SIV immunogens as potential vaccine candidates
• Design, coordinate and execute key in vitro and in vivo proof-of-concept studies including in mouse and NHP models
• Conduct in-depth characterization of cellular and humoral immune responses
• Develop, execute and troubleshoot assays.
• Identify, evaluate, and support relevant external collaborations
• Participate in multidisciplinary team efforts
• Present regular research updates to project teams and R&D management
Gilead is a fast-paced, data-driven, scientifically rigorous organization and the role will suit a scientist who is able to thrive in this type of environment.
Knowledge, Experience and Skills:
PhD in immunology or relevant life science discipline
Minimum of 2 years post-doctoral experience focused on innovative research in vaccine development and immunology with proven achievements in industrial or academic settings.
Strong level of understanding and expertise in vaccine design across a variety of vector platforms, viral immunology, and/or evaluation of immunotherapeutics.
Experience with a broad array of technologies to support assay development and discovery research is highly desired. Hands-on experience in immunogen design, vaccine vector biology and immunogenicity characterization, cell culture and/or virology techniques such as primary cell isolation and culture, immune cell functional assays including ELISpot assays, multi-color FACS, ELISA/Luminex, as well as molecular biology techniques such as RNA/DNA isolation, qPCR and cloning. Experience in assay development, ability to evaluate quality of the data, recognize anomalous results and interpret experimental outcomes is essential.
Excellent verbal communication and interpersonal skills. Ability to communicate effectively within the Virology group and functional groups within Research.
To apply, visit http://apptrkr.com/1384321
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact email@example.com for assistance.