Cancer Biology Postdoctoral Fellow

Cancer Biology Postdoctoral Fellow

Nicole Simone, MD

Philadelphia, PA, United States

Position
Description:
The Simone
Laboratory in the Radiation Oncology Department at Thomas Jefferson University
Hospital in Philadelphia, PA is seeking an outstanding post-doctoral fellow to work
in the area of cancer and radiation biology. Our laboratory focuses on using
metabolic manipulation such as dietary alterations, to improve standard cancer
therapy such as radiation and chemotherapy. Mechanistically, our focus is on
microRNA alterations and downstream effectors. Our laboratory has a focus on
hormonally responsive cancers such as breast and prostate cancer using both in
vitro and in vivo models. From the pre-clinical data generated in the Simone Laboratory,
we have now opened multiple clinical trials with hormone-driven cancer patients
which allows for the laboratory to evaluate translational endpoints of our
basic science research.

Experience
Required
: The candidate
must be highly motivated, independent and interested in our projects. The
candidate must have PhD in molecular biology, cell biology or a cancer related
field. Although not absolutely necessary, the ideal candidate will preferably
have some experience with caloric restriction, epigenetics, microRNA or
radiation biology. Expertise in microarray analysis, RT-PCR, ChIP, cloning,
mouse husbandry, in vivo tumor experiments are also a plus. The successful
candidate will of course have mentoring so that career goals can be achieved,
but must be able to independently generate hypotheses, design experiments to
test the hypothesis, performs routine and more difficult procedures, analyze
data and coherently present results in the form of presentations, abstracts,
manuscripts and the basis for grant writing, preparation and submission. In
addition, qualified candidates should have strong verbal and written
communication skills, and a demonstrated record of scientific achievement
through peer-reviewed publications. Successful, well-motivated candidates will join
a highly interactive, interdisciplinary team of researchers with diverse
backgrounds and expertise in a collaborative scientific environment. Preference
will be given to individuals with these skill sets who are now completing their
thesis work and have at least one high-impact publication.

Additional
Information: Please send a cover letter, curriculum vitae with full
bibliography and a statement of research interests to: Nicole Simone, MD;
Department of Radiation Oncology, Thomas Jefferson University Hospital; nicole.simone@jefferson.edu  http://www.jefferson.edu/university/jmc/departments/radiation_oncology/faculty/simone.html

Candidates may
be U.S. citizens, resident aliens, or nonresident aliens. Thomas Jefferson
University Hospital is an Equal Employment Opportunity and Affirmative Action
employer that values and fosters diversity throughout the entire organization.

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Position

Cancer Biology Postdoctoral Fellow