Principal Scientist in Neurology for Lundbeck Neuroscience

Principal Scientist in Neurology for Lundbeck Neuroscience

H. Lundbeck A/S

Copenhagen, Denmark

Our focus
Halting or even reversing the debilitating neurological diseases that affects an increasing number of people across the globe is as challenging as ever.

In Lundbeck we are dedicated to discovering new therapeutic possibilities for patients with neurogenerative diseases such as Alzheimer’s and Parkinson’s disease.

We believe that biological insights, experimental data, scientific excellence and collaboration are the cornerstones for becoming successful in creating novel effective treatments for these patients. Do you want to join us and change the lives of patients?

Join us to discover new treatments
Lundbeck Neuroscience is now looking for 2 experienced drug discovery scientists within Neurology, highly motivated by the outlook of discovering new treatments for diseases in the central nervous system.

The Neuroscience research organisation represent Biological research at Lundbeck. The main responsibility is to identify and validate drug targets, develop and support drug discovery with cell and animal based readouts needed for compounds or biologics to be developed into drug candidates and to develop strong translational packages. The organisation is divided into 4 departments, Signal Transduction, Proteinopathy, System Biology and Translational Biology. Disciplines represented range from molecular biology and biochemistry to in vivo electrophysiology and animal behavioural work.

The positions will be based in the in vitro part of the organisation, Department of Signal Transduction and Department of Proteinopathy. The overall focus in the departments is on molecular and cellular mechanisms and intracellular signalling with focus on Alzheimer’s and Parkinson’s Diseases as well as Schizophrenia and Depression.

Your job and key responsibilities
As a principal scientist, you will be working broadly across the Neuroscience organization in close collaboration with other academics and technicians and contribute with scientific leadership and key experimental data to our portfolio of drug discovery projects.
With your in-depth understanding of Alzheimer’s and/or Parkinson’s diseases you will drive development of new cellular models that report on target function enabling testing of hypothesis that link back to the symptoms and biochemical and cellular findings in patients.
You will guide project paths and decisions and you will continuously seek to extend and develop our scientific understanding and experimental platforms – internally and by identifying and maintaining academic and industry collaborations.

We offer
The opportunity to join a team of highly qualified and experienced colleagues that are on a quest of making new innovative medicines. We share a workplace with an open, science-driven, collegial and collaborative atmosphere. We focus on teamwork and individual professional development and you will be part of a global and specialized pharmaceutical company with approximately 5,000 employees specialized in psychiatric and neurological disorders.

Desired Qualifications for position in Proteinopathy
Our preferred candidate has the following professional and personal qualifications:
PhD in a relevant life science discipline with post-doctoral experience in Neuroscience
10+ years in Pharmaceutical research / Drug discovery
o Indebt knowledge and overview of biologies relevant for Neurodegenerative diseases, in particular Alzheimer’s and/or Parkinson’s disease
o Solid understanding of drug discovery and experienced in project management and scientific leadership.

Extensive hands-on experience in establishing and using cellular disease and/or mechanistic models to probe specific hypothesis and employing state of the art techniques within cellular signalling and phenotype profiling
A documented track record within the fields of intracellular vesicle trafficking, mitochondrial biology and/or phagocytosis is an advantage
Passionate about doing research and actively seeks scientific discussions of own data
Welcome the opportunity to work within an international and multidisciplinary team
Strong collaborative and team-player skills.

For further information, please contact Director Karina Fog on kape@lundbeck.com or by phone +45 36301311.

Desired Qualifications for position in Signal Transduction
Our preferred candidate has the following professional and personal qualifications:
PhD in a relevant life science discipline with post-doctoral experience in cellular and molecular neuroscience (academia or industry)
Strong insight into Alzheimer’s disease and/or other neuro-degenerative diseases
5+ years in pharmaceutical research including experience with devising and testing biological hypothesis in the context of drug discovery and target identification and validation
Experience with a broad range of in vitro assay techniques and extensive experience in establishing and using cellular disease mechanistic models to probe cellular phenotypes and signalling
Hands-on experience with RNAseq data or other types of omics data
Experience with establishing high content assays such as imaging based assays and biosensor based assays
Experience with leading project focused teams is an advantage
Basic data science skills (R or Python) is an advantage
Strong organizational, collaborative and team-player skills
Strong communicator in English, written and orally.

For further information, please contact Director Ib Vestergaard Klewe on ibve@lundbeck.com or by phone +45 36301311.

Your application
Please click on the link to apply for the job. Applications must be received no later than February 25th 2019. Your application and CV should not be sent via email. We also recommend that you have a look at our website www.lundbeck.com.

Please apply via recruiter’s website.

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