The postdoctoral fellow with a terminal degree (PhD, MD, DVM, etc.) will conduct basic/translational research aimed at elucidating the role of alternative mRNA splicing in resistance to cancer immunotherapy and in generating targetable neo-epitopes in leukemia. This project is funded by the recently awarded 5-year U01 grant from the National Cancer Institute as part of the Pediatric Immunotherapy Discovery and Development Network (PI-DDN) and Beau Biden Cancer Moonshot Initiative [https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/implementation/pediatric-immunotherapy-network#awarded-immunotherapy-projects]. The work will be carried out under the guidance of Dr. Andrei Thomas-Tikhonenko, Chief of Division of Experimental Pathology at the Children’s Hospital of Philadelphia (CHOP).
CHOP shares a contiguous campus with the Perelman School of Medicine at the University of Pennsylvania, with ample interactions with the NCI-designated Abramson Cancer Center, Institute for Immunology, and other academic entities.
Strong candidate will have considerable experiences in one of the following fields: RNA biology, cancer genetics, hematologic malignancies, immunotherapy, and bioinformatics. However, recent graduates with published record of accomplishments in related areas will be considered as well, as long as they have the thirst to prove themselves in a highly collaborative and dynamic research environment.