The Roslin Institute
£33,199 – £39,609pa – fixed term for 36 months
A post-doctoral fellowship is available in the University of Edinburgh with Professor J. Ross Fitzgerald and colleagues (https://www.ed.ac.uk/roslin/lbep). Antimicrobial resistance (AMR) is a global veterinary and public health issue. The 3 year-funded project involves a grouping of microbiologists, bioinformaticians and veterinary and human medical clinicians in the Roslin Institute, University of Edinburgh. We have demonstrated the capacity for Nanopore-based whole genome sequencing of clinical samples without the need for culture, to allow rapid diagnosis of bacterial infections and prediction of antibiotic sensitivity. The successful candidate will further develop the sequence-based technique which will be formally tested on veterinary patients with infections in a clinical setting. In addition, the new approach will be applied to studies of bacterial evolution of AMR during infection. Candidates should have experience of Nanopore sequence generation and analysis and a PhD (or near completion) in bacterial genomics/computational biology. The Roslin Institute is a world-class centre for biomedical research of relevance to both animal and human health with a strong focus on infectious diseases. The Institute has access to state of the art research facilities for imaging, proteomics, and genomics, including high-throughput sequencing and is a major partner within Edinburgh Infectious Diseases which represents one of the largest groupings of infectious disease scientists in Europe, with a major strategic priority of tackling the global AMR crisis (https://www.ed.ac.uk/edinburgh-infectious-diseases/amr).
This post is available on a fixed term basis, with a working pattern of 35 hours per week for 36 months.
Informal enquiries: Ross.Fitzgerald@ed.ac.uk
Relevant selected references:
Votintseva et al, Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples. J Clin Microbiol. 2017 55(5):1285-1298.
Closing Date: 26th February 2019
For further particulars and to submit an application visit our website www.vacancies.ed.ac.uk