Salary: Grade 6: £28,660 - £34,189 p.a.
We are seeking a motivated and enthusiastic Research Assistant to join the research group of Professor Paresh Vyas (www.imm.ox.ac.uk/research/units-and-centres/mrc-molecular-haematology-unit/research-groups/vyas-group-normal-and-malignant-haematopoiesis-lab). The groups research interests focus on understanding how genetic and epigenetic changes disturb normal stem and progenitor haemopoietic differentiation to lead to clonal haemopoiesis myelodysplasia (a pre-leukaemic disorder) and acute myeloid leukaemia (the most common aggressive adult leukaemia). Allied to this the laboratory conducts translational research to improve existing treatment and develop novel therapies for these devastating diseases.
Working as part of a team, you will study patient samples to define genetic (next generation sequencing) and epigenetic (ATAC-Seq and ChiP-Seq) changes in flow sorted leukaemic populations. You will study measurable residual disease in patient samples from clinical trials.
You will hold a degree minimum 2:1 in biology, genetics, biochemistry or a biomedically-related area and have proven experience in molecular and cellular biology methods, next generation sequencing and FACS analysis. Experience of coding and bioinformatic analysis is desirable. The ability to work both as part of a team and independently, a methodical approach to laboratory work with good manual dexterity and excellent organisational and communication skills are essential.
The post is fixed-term, funded by the NIHR Oxford Biomedical Research Centre until 31 March 2021, with an immediate start.
Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application
The closing date for this position is 12.00 noon on 20 February 2019. Interviews will be held in early March 2019.