Three Postdoc Positions in Membrane and Inositol Pyrophosphate Signal Transduction

Three Postdoc Positions in Membrane and Inositol Pyrophosphate Signal Transduction

University of Geneva - Faculty of Sciences

Geneva, Switzerland

Three ERC / HHMI funded postdoc positions are available in the group of Michael Hothorn at the University of Geneva. We use a combination of structural biology, quantitative biochemistry and genetics to dissect novel signalling pathways in plants.

Postdoc position: Structural biology of inositol pyrophosphate signal transduction.
The successful candidate will dissect how inositol pyrophosphate signaling molecules interact with novel signaling proteins and protein complexes to control plant development.

Postdoc position: Molecular characterization of inositol pyrophosphate signalling pathways in Arabidopsis.
The successful candidate will characterize how inositol pyrophosphate signaling molecules relay changes in the plant’s nutrient status to developmental adaptations.

Postdoc position: Structural biology of membrane receptor kinase signaling complexes.
The successful candidate will identify novel receptor – ligand pairs and study the ligand-binding and receptor activation mechanisms of plant-unique membrane receptor kinases and their signaling complexes.

We offer
to work in a multidisciplinary team interested in cell signaling in plants. The group has a strong background in protein crystallography, quantitative biochemistry, plant genetics and cell biology. State-of-the-art equipment for plant genetics and cell biology, for eukaryotic protein production , protein purification (6xFPLCs, 1xHPLC), biochemical analysis (2xITCs, SPR, SEC-MALLS) and structural characterization (crystallization platform, Talos Arctica) is available in the lab and department. English is the working language of the laboratory.

Your profile
We are looking for highly motivated candidates with a PhD in either biochemistry / structural biology or plant genetics / cell biology. You are less than 12 month post-PhD defense with a proven track record (one+ first-author paper) and a keen interest in signal transduction mechanisms. PhD students approaching their thesis defense are encouraged to apply. Excellent oral and written communication skills are required.

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Three Postdoc Positions in Membrane and Inositol Pyrophosphate Signal Transduction