The Charité – Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.
POSTDOC (w/m/d) (HIV Research)
Ref. no.; CC05-31.18
Institute of Virology
The Research Group Innate Immunity and Viral Evasion (headed by Prof. Dr. Christine Goffinet, formerly TWINCORE, Hannover) at the Institute of Virology of Charité is hiring a highly motivated, scientifically excellent, team-minded and experienced postdoc (w/m/d). Our research focuses on cell-intrinsic immunity against viral human-pathogenic infections, with a focus on HIV and arboviruses. Basic research on mechanisms of cellular antiviral restriction factors and sensing, and intercellular communication are progressively translated towards the development of therapeutic and preventive intervention strategies.
Your area of responsibility
Tasks comprise research on cell-intrinsic mechanisms that modulate the course of HIV-1 infection and latency. The goal of the project is the characterization of cellular sensing and restriction strategies in primary CD4+ T-cells and macrophages, the key target cell types of HIV-1 in vivo. In addition, we aim at elucidating respective viral evasion and antagonistic mechanisms. We are also interested in genetic polymorphisms which potentially shape innate immunity against viral infections. The experiments are performed in established primary cell models and using HIV-1 patients´samples. The project benefits from several DFG grants.
Our team is equipped with a brand-new laboratory and a large portfolio of state-of-the-art methodology, including automated FACS, nucleofection, BSL3 confocal live cell imaging, disposes of established techniques of cell biology, molecular biology and immunology (primary cells, cocultures) and has access to core platforms of the Charité/BIH (Genomics, Bioinformatics, Biobank). We offer a highly relevant biomedical research project in an interactive group and a stimulating and internationally highly competitive environment.
Academic degree (completed Master´s Thesis for natural scientists) in human or veterinary medicine, biology or other life science
Doctorate/PhD in virology or immunology with visible publication record
Fluent Englisch, German language desirable
High degree of self-initiative, team-working ability, analytical thinking, excellent organisation and communication skills, self-responsibility
Knowledge and experience in animal experimentation and/or cell/molecular biology
Experience in experimental work with BSL3 pathogens
Experience in drafting and writing of manuscripts and research grants is required
Expertise on high-end confocal microscopy is desirable
Experience in teaching and supervision of students (w/m/d) is welcome
Length of employment
Working time (hrs./week)
Pay (pay scale)
Acc. To collective agreement:
TVöD VKA – K
Employees are grouped into pay scales according to their qualifications and personal requirements. You can find our collective bargaining agreements (Tarifverträge) here: https://www.charite.de/en/careers
Application deadline: 25.01.2019
Please send your application quoting the reference number to:
Charité – Universitätsmedizin Berlin
Institut für Virologie
Frau Prof. Dr. Christine Goffinet
D-10117 Berlin oder per Mail(<10MB):
Mail & name of contact person:
Prof. Dr. Christine GOFFINET