PhD Student (gn) Immunology / Cell Biology

PhD Student (gn) Immunology / Cell Biology

Universitatsklinikum Munster

Munster, Germany

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. In return there are many possibilities open for you so that you may develop with them.

The Department of Dermatology, Experimental Dermatology and Immunobiology of the Skin is looking for a

Scientist or PhD Student (gn*) Immunology / Cell Biology
Ref.: 03359

Part-Time with 65%
Salary according to TV-L

(*gn=gender neutral)

starting as soon as possible with an initial fix-term contract for three years including the possibility of contract extension.

The Department of Dermatology is conducting research in the fields of systemic autoimmunity, inflammatory skin diseases (atopic dermatitis, psoriasis, lupus erythematosus). At the Center for Experimental Dermatology and Immunobiology of the Skin we have a long-standing interest in investigating the regulation of antibacterial, antiviral and anti-tumoral immune reactions. Additionally, we focus on analyzing central mechanisms, which control the interaction between environment and organism as well as signaling pathways responsible for the transmission of external stimuli in immune responses.

We are looking for a colleague to participate in our research project to better understand the role of TNF/TNF-receptor-mediated signaling pathways during the progression of inflammatory skin diseases and the interaction of pathophysiologically relevant cell populations. For this purpose already available and well-established animal models with cutaneous overexpression or deletion of different TNF-receptors as well as complex cell-culture systems and whole transcriptome (RNA-seq) or proteome analyses will be used. After having identified relevant mechanisms in vitro or in inflammatory models the findings shall be validated in patient samples.

Your responsibilities:

  • Phenotypical and functional characterization of immune reactions in systemic autoimmunity or inflammatory skin diseases in vivo
  • Mouse experiments
  • Imaging analyses to investigate the interaction of immune cells, neuronal and epithelias cells
  • Multicolor flow cytometry and FACS-based cell sorting
  • RNA-sequencing of immune cell populations, epithelial and neuronal cells

The ideal candidate:

  • holds a Diploma or MSc degree in a related subject (biology, biotechnology, molecular medicine or similar)
  • has experience in handling laboratory animals
  • has solid knowledge and laboratory experience in the fields of molecular biology, cell biology or immunology
  • has experience in flow cytometry, in vitro imaging or RNA sequencing. This is desired but not mandatory.
  • is highly motivated and committed and shows strong team-working skills as well as the ability to work independently.

We offer modern laboratories equipped with state-of-the-art instruments, participation in research networks and versatile and challenging professional activities in a high-performing and motivated team. In addition, we offer the possibility of promotion and would like to support it.

For more information on the advertised position please contact Stefanie Detering, +49 251-83-58640 or stefanie.detering@ukmuenster.de.

We are looking forward to receiving your complete online application via our career portal until February 3rd, 2019. For further information please refer to www.karriere.ukmuenster.de.

The UKM supports compatibility of career and family and is certified as family-conscious organization. As a basic principle there is the possibility of part-time work. Applications of women are specifically invited; in the case of similar qualifications, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference.

Please apply via recruiter’s website.

Quote Reference: 03359

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