Job title: Project Research Scientist
Location: The Francis Crick Institute, Midland Road, London
Contract: Fixed term, (2 years)
Salary: Competitive with benefits, subject to skills and experience
Vacancy ID: 9528
The Research Group
The Malaria Immunology Laboratory, headed by Dr Langhorne, studies the immune response to the malaria parasite, including the components involved in protection from infection and those that contribute to Malaria induced pathology, as well as, the molecules of the parasite that stimulate these responses in experimental models and in humans.
The successful candidate will join the team lead by Jean Langhorne. The group is interested in studying pathways of immunity and virulence in an experimental model of malaria. This project will concentrate on the pir (Plasmodium interspersed repeat) multigene family in these processes. The project will include establishing expression and location of PIR in the blood stages of the life cycle, transfection of the rodent malaria parasite, Plasmodium chabaudi, and the effects of overexpression and knockout of pir genes on the interaction with the mouse immune system. This will also involve working with other scientists from the group to analyse RNA-seq, single cell seq, and immunofluorescence data.
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
- If you are interested in applying for this role, please apply via our website.
- The closing date for applications is 04 February 2019 at 23:30.
- All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.