Postdoctoral position in the area of DNA Materials Systems

Postdoctoral position in the area of DNA Materials Systems

Albert-Ludwigs-Universitaet Freiburg

Freiburg, Germany

Albert-Ludwigs-Universität Freiburg

The Cluster of Excellence Living, Adaptive and Energy-autonomous Materials Systems (livMatS) is offering a

Postdoctoral position in the area of DNA Materials Systems

The Cluster of Excellence livMatS develops completely novel, bioinspired materials systems that adapt autonomously to various environments and harvest clean energy from their surroundings. The intention of these purely technical – yet in a behavioral sense quasi-living – materials systems is to meet the demands of humans with regard to pioneering environmental and energy technologies. The societal relevance of autonomous systems and their sustainability will thus play an important role in their development. The research program of livMatS is characterized by highly interdisciplinary collaboration between researchers from a broad range of fields including engineering, chemistry, physics, biology, psychology, the humanities, and sustainability sciences.

In the framework of the Cluster, the Walther group at the Institute for Macromolecular Chemistry at the University of Freiburg is searching for a highly motivated postdoctoral researcher with a background in chemistry, soft matter science or DNA nanosciences to work on “Chemically Fueled, Non-equilibrium DNA-based Self-Assembling Materials Systems” with an overall aim to create life-inspired, chemically fueled, non-equilibrium DNA systems, that mimic the principles and dynamics of microtubules and other dynamic cytoskeleton fibrils. The resulting systems and materials are expected to feature unexpected steady-state dynamics (i.e. dynamic instabilities) as well as limited lifetimes in autonomous systems programmed through the consumption of chemical fuels. The project is strongly interdisciplinar and connects DNA nanotechnology, polymer and colloid science with non-equilibrium self-assembly, and physical chemistry. The project can be developed in the direction of increasing structural complexity (e.g. DNA origami), higher chemical reaction network complexity (e.g. advanced feedback mechanisms) or in the direction of materials with an emphasis on hydrogels and soft robotics application.

We provide you with an inspiring and collaborative team atmosphere, cutting-edge infrastructure and ample opportunities to develop first steps towards an individual scientific profile.

Selected recent references on the topic:

  1. “Materials Learning from Life: Concepts for Active, Adaptive and Autonomous Molecular Systems” Chem. Soc. Rev. 46, 5588 (2017).
  2. “Antagonistic Enzymes in a Biocatalytic pH Feedback System Program Autonomous DNA Hydrogel Life Cycles” Nano Lett. 17, 4989 (2017).
  3. “Biocatalytic Feedback-Driven Temporal Programming of Self-Regulating Non-Equilibrium Peptide Hydrogels” Angew. Chem. Int. Ed, 54, 13258 (2015).
  4. “3D DNA Origami Cuboids as Monodisperse Patchy Nanoparticles for Switchable Hierarchical Self-Assembly” Nano Lett. 16, 7870 (2016).
  5. “Pathway-Controlled Formation of Mesostructured all-DNA Microgels and their Superstructures Nat. Nanotech., 13, 730 (2018).

More information on the group can be found here: https://www.walther-group.com/

As an ideal candidate you are creative, highly self-motivated, ambitious and communicative to excel in scientific challenges, and have a proven track record with innovative publications in a relevant field (polymer/colloid chemistry/physics, soft matter, DNA nanoscience). A keen interest in physical chemistry, advanced analytics (in particular microscopy) and working with biological components is a must. Previous research experience in DNA-based materials, non-equilibrium self-assembly and enzymes is a plus.

Please hand in:

— Letter of intent detailing why you are interested in this specific project and how your previous research qualifies you for the project (up to 1,500 words)

— Curriculum Vitae with list of publications (if applicable)

— Certified copies of your university degree(s) with grades (BA and MA certificate / Diploma certificate and transcript / doctoral certificate)

— Short summary of your doctoral thesis (up to 1,000 words)

— Work sample (chapter from recent thesis or journal article, up to 5,000 words)

— Suggestion of two referees with contact details

The position is limited to 28.02.2021. After positive evaluation, an extension until 28.02.2022 is possible.

Your documents will not be returned after the application process. For this reason, please submit copies only.

The salary will be determined in accordance with TV-L E13.

Please send in a complete and convincing application including the supporting documents specified above and citing the reference number 00000265, by January 31th 2019 at the latest. Please send your application to the following address in written or electronic form:

Albert-Ludwigs-Universität Freiburg

Dr. Monika Schulz

Freiburger Zentrum für interaktive Werkstoffe und bioinspirierte Technologien (FIT)

Georges-Köhler-Allee 105

D-79110 Freiburg

Kennwort: livMatS

E-Mail (please only one pdf file):

positions@livmats.uni-freiburg.de AND andreas.walther@makro.uni-freiburg.de

For further information, please contact Herr Prof. Dr. Andreas Walther on the phone number +49 761 203-6271 or E-Mail andreas.walther@makro.uni-freiburg.de.

Wichtige rechtliche Hinweise: www.uni-freiburg.de/stellen

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Postdoctoral position in the area of DNA Materials Systems