We study how immune and other cell types detect wounds or wound-like lesions, such as tumors, or organ damage. To this end, we combine intravital imaging, genetic, biochemical, biophysical, and omics approaches in live zebrafish, cell culture, and reconstituted systems (Niethammer et al., Nature, 2009; Enyedi et al., Nature Cell Biology; 2013; Enyedi et al., Cell, 2016; Huang et al., Immunity, 2018).
Project areas include:
- The biomechanical regulation of early inflammation during wound detection and confined leukocyte migration in tissues.
- Inflammatory lipid signaling during wound healing and cancer.
- Visualizing physiological gradients of inflammatory mediators during tissue damage and infection.
We are a young, interdisciplinary team that embraces new ideas, approaches, and rigorous, quantitative research. Candidates from cell biology, biophysics, biochemistry, immunology, and bioengeneering are encouraged to apply. Experience with zebrafish is not required.
- Positions are NIH-funded for two years and longer depending on performance.
- Internal postdoctoral fellowships are available for productive candidates.
- Subsidized Manhattan housing is available.
- Salary levels are competitive.
For more information, please visit our website (https://www.mskcc.org/research/ski/labs/philipp-niethammer) or contact Philipp Niethammer.