The candidate will lead multiple early-stage small-molecule drug discovery programs. He/she will work in tandem with the Lead Medicinal Chemist towards the discovery of validated hits, optimized lead compounds or (pre)clinical candidate drugs. You will be expected to design and implement experiments to investigate the pharmacological activity of compounds (e.g. target, hit and assay validation, identification of biomarkers, elucidation of mechanism of action). The candidate will oversee and execute lab-based activities in support of the project on a day-to-day basis, as well as manage and follow-up all biology-related scientific and non-scientific aspects of his/her projects (including planning, timelines and budget). The candidate will report on progress of the project and ensure an overall good communication between the internal and external partners involved. The candidate will directly report to the Director of Drug Discovery (Biology), and work in close collaboration with the Director of Medicinal Chemistry.
• You hold a PhD degree in Biology, Biochemistry, Medicine, Biomedical Sciences, Bio-engineering, Pharmacy or equivalent; in addition you have productive post-doc experience, illustrated by high-quality publications
• You have a broad knowledge of biomedicine (preferably in the fields of metabolic or cardiovascular disease, fibrosis, or immunity) and pharmacology; and you are able to critically evaluate new project opportunities. Ideally, you have experience in small-molecule drug discovery.
• You are a team player who can operate independently with attention for quality and details and at the same time be outgoing and a strong networker;
• You are an ambitious, hard and diligent worker willing to take responsibility and learn fast;
• You are pro-active, goal oriented and can handle deadlines and pressure while taking responsibility for multiple projects at the same time;
• You are communicative, diplomatic and fluent in English (oral and written);