Postdoctoral Associate - Elucidating Structures of Novel CRISPR-Cas and Cas-Related Proteins

Postdoctoral Associate - Elucidating Structures of Novel CRISPR-Cas and Cas-Related Proteins

Howard Hughes Medical Institute (HHMI)

Berkeley, CA, United States

Job Description

About HHMI

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit to learn more about working at HHMI.


Postdoctoral Scholar position at UC-Berkeley, Doudna Laboratory:

Elucidating Structures of Novel CRISPR-Cas and Cas-Related Proteins

The Departments of Molecular and Cellular Biology (MCB) and Chemistry at The University of California, Berkeley invite applications for a Postdoctoral Scholar - Employee position starting in early 2019. This position will continue the history of structural excellence in the Doudna lab through either/both crystallographic and cryoEM techniques. The ability to both lead independent projects and provide a supportive role to elucidate the structures of biomolecules with collaborators within and beyond the Doudna lab are essential.

A Postdoctoral Scholar with structural expertise in this position will have the freedom to define their top research goals and discern the most exciting research avenues based on novel discoveries coming out of the lab. Additionally, there are a number of ongoing projects in the Doudna lab that would greatly benefit from collaboration to complete structural studies.

This postdoctoral position requires technical expertise to prepare samples, collect structural data, create models of likely structural conformations, and interpret the results relative to the biology, particularly in the realm of genome editing. This position requires someone who is highly motivated and driven to pursue independent projects and research goals related to structural studies. Further, they will be required to work as a part of a dynamic team in collaboration with other members of the lab to collect structural information relevant to ongoing projects, and to aid in correct interpretation of the obtained data. This person will work in the laboratory of Jennifer Doudna (MCB). Access to HHMI-funded cryoEM facilities will be provided.


A Ph.D. with a strong background in biochemistry and genetics (or related disciplines) is required. Experience with working in teams, as well as an ability to work independently, is essential.  Applicants should submit a cover letter, CV, and a summary of research experience. Three (3) confidential letters of reference will be requested. Minorities and women are especially encouraged to apply.


HHMI is an Equal Opportunity Employer

Required Skills

Required Experience

Please apply via recruiter’s website.

Quote Reference: Howard Hughes Medical Institute (HHMI)-hhmi-918-908