The Sylvester Comprehensive Cancer Center at the University of Miami is currently seeking a highly motivated postdoctoral fellow with in-depth knowledge and extensive skills in cellular and molecular biology to join the lab. The candidates should demonstrate expertise in various lab techniques including cell culture and molecular biology assays (molecular cloning, cell proliferation assay, subpopulation analysis by FACS, stable and transient transfection, use of shRNA and viral constructs), preparation and analysis of DNA and RNA (preparation of plasmids, regular PCR and RT-PCR), chromatin immunoprecipitation (ChIP) assays, biochemical assays (ELISA, immunoblotting, Co-IP). Prior experience in epigenetics is preferred but not required. Prior experience in hematopoiesis/leukemia models, molecular biology, cancer genetics or epigenetics, and/or development of animal models is required. It is expected that the candidate will have the ability to work independently, design experiments with appropriate controls, collect and tabulate data, publish and present results, as well as to participate in the training of graduate and rotation students in a research laboratory setting. Projects will include in vivo and in vitro modeling of candidate genes to identify epigenetically silenced genes that contribute to the development of hematopoietic malignancies and characterization of c andidate genes using in vitro and in vivo systems.
Applicants should hold a PhD and/or MD degree and have strong molecular biology or cancer biology skills. Previous experience with epigenetics, cancer modeling or hematopoiesis is preferred. Evidence of scholarly ability (record of publication in peer-reviewed journals, etc.) must be presented. Ability to communicate in written and spoken English is absolutely required. The successful candidate will be working in a collaborative environment that includes wet bench cancer biologists and computational biologists.
KNOWLEDGE SKILLS AND ABILITIES:
- Solid training in molecular or cancer biology
- Strong laboratory skills
- Prior experience with mouse models is preferred
- Understanding of epigenome and cancer biology
- S trong oral and written communication skills
- Ability to collect, organize, summarize and report biological data
- Ability to design biological experiments, with appropriate controls and conditions to address specific biological questions
- The ability to work both independently and in a team environment
- Ability to write manuscripts independently
EDUCATION & EXPERIENCE:
PhD and/or MD degree and have strong molecular biology or cancer biology skills. Excellent communications skills in English (both verbal and written).