Salary: Grade 7: £32,236 - £39,609 p.a.
Vaccines are one of the worlds most important public health achievements, yet their life-saving potential has not been realised for many emerging epidemic threats. Emerging pathogen outbreaks disproportionately affect low-income countries, where the risks and needs are often greatest, putting immense pressure on already fragile health systems and economies. The Jenner Institute (University of Oxford), in partnership with Janssen Vaccines, has secured funding from the Coalition for Epidemic Preparedness (CEPI http://cepi.net/) to continue development of replication-deficient simian adenoviral vectored vaccines against three emerging pathogens: Middle East Respiratory Syndrome (MERS) Coronavirus, Nipah virus and Lassa virus.
We seek to recruit a postdoctoral scientist to support the Jenner Institutes on-going programme of vaccine development against emerging pathogens. You will have a PhD (or near completion) and will be responsible for the development of antibody assays which will be suitable for use in preclinical development and in Phase I and II clinical trials of vaccines against MERS, Nipah and Lassa. The primary focus will be to develop, optimise, standardise and then validate antibody assays to be used as the primary readout in these clinical trials. Additionally, preparation of human monoclonal antibodies against emerging pathogens will be explored.
The Jenner Institute has a strong record of attracting external grant funding, a robust publication record, and the programmes for vaccine development toward emerging pathogens have expanded significantly in recent years. We aim to foster scientific excellence within a welcoming and progressive environment. The postholder will play a key role in the Emerging Pathogens Vaccine Groups on-going programme of work, under the direction of Professor Sarah Gilbert, supervised by Associate Professor Katie Ewer. You will be a highly organised, motivated individual with proven experience in immunology assessment, particularly of antibody based assays. Excellent communication skills with the ability to present results clearly and logically, working co-operatively as part of a team as well as independently, are also essential capabilities for this post. You will adapt and develop new scientific techniques and experimental protocols; gather, analyse, and present scientific; collaborate in the preparation of scientific reports and journal articles and present papers and posters; and contribute to wider project planning, including ideas for new research projects. You will work closely with the clinical team as there is a major translational emphasis, with full integration of the clinical and laboratory teams. GCP experience would be advantageous but is not essential. The work will also include collaboration with a variety of external partners in Europe, the USA and the Middle East.
The post is full-time and fixed-term for up to 2 years in the first instance. The postholder will be based at the Jenner Institute, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ.
The closing date for applications is 12.00 noon on Friday 11 January 2019.