Postdoctoral Research Fellow in Computational Biology, Systems Biology – Modeling of Vector-Borne Diseases

Postdoctoral Research Fellow in Computational Biology, Systems Biology – Modeling of Vector-Borne Diseases

University of California, San Diego (UCSD)

La Jolla, CA, United States

Our lab at the University of California, San Diego unravels the fundamental principles of host-microbe interactions by integrating multi-omics data with computational models. For this particular project we are interested in how the genotype and the environment determine dynamic interactions between microbes and their changing hosts. The goal is to elucidate the basis for these interactions and to develop rational interventions for disease prevention.

We are looking for an outstanding postdoctoral research fellow with a background in Systems Biology/Computational Biology to join a multi-disciplinary team. The ideal candidate would have the following qualifications:

o PhD in Systems Biology/Computational Biology, related discipline, or strong background in bioinformatics approaches
o Relevant experience and proven track record in modeling of biological systems and constraint-based modeling
o Very good programming skills and knowledge of programming languages (e.g. Python, MatLab, or R)
o Good general knowledge of biology and biochemistry
o Knowledge of photosynthesis and/or plant biology a plus
o Ability to work within an interdisciplinary research team
o Desire to work synergistically in direct collaboration with experimentalists
o Open-minded, innovative and communicative
o Excellent English skills

The successful candidate will work collaboratively within an international and interdisciplinary research team of molecular biologists, microbiologists, computer scientists, and plant biologists. UC San Diego is a top-ranked research institution with a strong focus in microbiome research and faculty and students cherish a highly collaborative research culture. The candidate will use genome-scale metabolic models of microbes and hosts to study disease outcomes and design targeted interventions.

o Reconstruction and validation of genome-scale models to interrogate vector-born disease.
o Generation of host-microbe model and interrogation of community models.
o Close collaboration with experimental/plant biologists to understand the biological systems
o Design and analysis of computational models of various aspects of vector-born diseases.
o Development of mechanistic hypotheses and design of intervention strategies.

Salary is according to the UC funding guidelines. UC San Diego is an Equal Opportunity/Affirmative Action Employer with a strong institutional commitment to excellence through diversity. All qualified applicants will receive consideration for employment without regard to gender, race, color, religion, sex, sexual orientation, national origin, disability, age or protected veteran status.UCSD is an equal opportunity employer and supports gender equality.

Please send your application including all documents by e-mail (not acceding 5 MB in total file size) to Karsten Zengler at with “_postdoc position vector-borne disease_” as subject line.


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Postdoctoral Research Fellow in Computational Biology, Systems Biology – Modeling of Vector-Borne Diseases