Postdoctoral Research Associate

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford

Oxford, South East England, United Kingdom

Salary: Grade 7: Salary in the range £32,236 - £37,345 p.a.

We are seeking to recruit a talented, proactive Postdoctoral Research Associate to join Dr Gillian Farnie in NDORMS and the Structural Genomics Consortium, based at the Botnar Research Centre, Oxford. You will deliver research as part of the innovative Medicines initiative (IMI) ULTRA-DD project, a program, which aims to create an open access consortium that provides industry with a stream of high quality target-disease associations and tools to study them. Current probe families include YEATS, nudix hydrolases and deaminase.

You will work in an exciting collaborative environment to develop and establish cell based assays to validate novel chemical probes (generated by the SGC). Innovating novel cell based screening assay to assay breast cancer cell biology and cancer stem cells in the presence of the tumour microenvironment inc. fibroblasts, adipocytes and immune cells. Such assays will be used to validate and discover new targets for drug discovery.

A PhD in a relevant area of biological sciences, good publication record and excellent communication skills including the ability to form collaborations, prepare research for publication and present at national and international meetings are essential for this role. You will have experience and expertise in molecular biology techniques including; flow cytometry, cloning, rtPCR, Western blotting, genome editing and cell biology, including 3D and co-culture models, measuring a variety of phenotypic effects. Experience with patient derived samples, cancer stem cells and high content screening would be desirable.

This is a full-time fixed-term appointment until 29 February 2020.

You will be required to upload a supporting statement and CV as part of your online application.

The closing date for applications is 12.00 noon on Wednesday 19 December 2018.

Please apply via recruiter’s website.

Quote Reference: University of Oxford-itox_ac-138157