The Masonic Medical Research Institute is a not-for-profit institute dedicated to improving the health and quality of life for all. The institute’s primary mission is to conduct high quality basic and clinical research aimed at generating knowledge and information necessary for development of the medical cures and treatments of tomorrow. The institute is also committed to providing education and training to basic scientists, clinical researchers and students who will perpetuate and extend the fight against disease.
The following 2 Postdoctoral positions are available:
1. Post-doctoral position immediately available at the Masonic Medical Research Institute to examine molecular genetic and epigenetic mechanisms controlling cardiac hypertrophy and heart failure. A dedicated, self-motivated scientist holding a Ph.D. or equivalent degree with experience in molecular biology, biochemistry and animal handling (preferred) is sought. Comprehensive novel technologies including chromatin immunoprecipitation, RNA-seq, state of the art imaging among others will be used in iPSC, primary cardiac cells and genetically modified mice to study abnormal gene regulation, chromatin structure and molecular signaling in the diseased heart. The candidate will be offered a competitive salary and is invited to email his/her CV along with email addresses and phone numbers of three references
2. A postdoctoral research position in the areas of venous biology with particular emphasis on thromboembolism and molecular imaging is available in the laboratory of Jason McCarthy, PhD at the Masonic Medical Research Institute in Utica, NY. This position in heavily multidisciplinary, requiring the candidate to take leading roles in coordinating the research efforts of chemists, vascular and fibrosis biologists and clinicians to translate novel nanomedicine and imaging platforms to elucidate mechanisms and pathobiology of pulmonary embolism and deep vein thrombosis and its sequalae. The candidate will collaborate with top DVT, PE biologists, chemists and laboratory scientists in a collegial work environment infused with intellectual rigor.
Providing imaging analysis and advice for on-going laboratory projects, brainstorming with other team members to develop interdisciplinary solutions to existing problems, contributing to the writing of grant proposals, and the development of new biomedical imaging techniques in the context of understanding PE and DVT biology. Candidate should also be experienced in histopathology techniques, such as immunohistochemistry and immunofluorescence, and molecular biology techniques to validate targeting and efficacy of nanomedicine and imaging platforms.
• Ph.D. in a biomedical discipline, biology, thrombosis and vascular biology, or related fields.
• A solid understanding of thrombosis, platelet, fibrosis, and/or pulmonary biology and inflammation is required.
• Experience in fluorescence imaging and image analysis is necessary optical, ultrasound, MR, CT and PET imaging, molecular biology of inflammation, animal models of deep vein thrombosis, cell culture, pharmacokinetics, biodistribution and/or image analysis (e.g., ImageJ, FIJI, MATLAB, OsiriX) is helpful but not required.
• Solid foundation in the fundamentals of statistics, experimental design and data analysis, and the ability to approach problems with scientific rigor.
• Excellent communication skills with a publication record as an objective evidence of scientific and research involvement/potential/achievement.
• Candidates must be energetic, friendly, self-motivated and capable of multitasking.
The candidate will be offered a competitive salary and is invited to email his/her CV along with email addresses and phone numbers of three references