Research Fellow

Research Fellow

University College London (UCL)

London, United Kingdom

Great Ormond Street Institute of Child Health

London

Research Fellow

Full Time

The appointment will be on UCL Grade 7. The salary range will be £35,328 – £42,701 per annum , inclusive of London Allowance.

The aim of the project is to understand how genetic variation, common and rare, affects molecular phenotypes in human induced pluripotent stem cells (iPSC) and neuronal cell types derived from them, and how this affects the use of iPSCs as models for rare genetic diseases. The project builds on resources and results from the Human Induced Pluripotent Stem Cell Initiative (http://www.hipsci.org/). The successful candidate will analyse genetic, transcriptomic and epigenomic data from these cells to investigate molecular differences in disease phenotypes arising from their genetic background. The ultimate goal of the project is to improve the accuracy of iPSC-based disease models and enable clinically relevant findings.

This post is available for 24 months in the first instance with the possibility of further extension.

Key Requirements

We are seeking a creative and highly motivated individual with prime interest in genomics. Candidates should have a PhD in bioinformatics, computational or evolutionary biology, statistics or related genomic disciplines. The ideal candidate will have experience in at least one of the areas above, and a strong interest in the others. Previous work in translational bioinformatics (theoretical or analytical) is a plus. Experience with large-scale genomic datasets and databases, next-generation sequencing data, and strong programming and quantitative skills are required.

For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1736996

If you have any queries regarding the application process please contact ICH HR on ich.hr@ucl.ac.uk quoting the job reference number.

Closing Date: 30 November 2018

Latest time for the submission of applications: 23:59.

Interview Date: TBC

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Quote Reference: 1736996

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