Postdoctoral Research Assistant - Molecular Mechanisms Underlying Late Blight Resistance by Pip1 Immune Protease of Tomato

University of Oxford

Oxford, South East England, United Kingdom

Salary: Grade 7: £32,236 - £39,609 p.a.

The Department of Plant Sciences is seeking to recruit a Postdoctoral Research Assistant for 2 years starting January 2019, funded by BBSRC. This grant is held by Professor van der Hoorn and the work is to be conducted in his lab in the Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, OX1 3RB. The research topic is ‘Molecular mechanisms underlying late blight resistance by Pip1 immune protease of tomato’.

Responsibilities include: Select and characterise homozygous tomato plants lacking Pip1. Infect tomato plants with P. infestans. Isolate secreted proteomes and analyse this by various proteomic techniques. Identify cleavage events using TAILS, PROTOMAP and quantitative proteomics. Create uncleavable substrates by mutagenesis of putative cleavage sites. Subject agroinfiltrated plants to disease assays using P. infestans. Work with other team members within the Plant Chemetics research program. Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines. Develop ideas for generating research income, and present detailed research proposals to senior researchers. Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.

The postholder should have a PhD or equivalent, or be close to completion, in a relevant area. Strong track record in writing and publishing scientific manuscripts. Able to plan and manage large experiments. Experience with disease assays using fungal/oomycete plant pathogens. Experience in molecular cloning. Experience with working in a research team. Extensive expertise in protein work (extraction, western blot, pull downs, etc.). Experience with proteomics. Experience with P. infestans. Experience in working with proteases.

Informal enquiries should be directed to Professor van der Hoorn at:

The closing date for applications is 12.00 noon on Friday 30 November 2018.

Please apply via recruiter’s website.

Quote Reference: University of Oxford-itox_ac-137709