2 Post-doctoral researcher (computational & wetlab) in the research group “Evolutionary Developmental Biology”

2 Post-doctoral researcher (computational & wetlab) in the research group “Evolutionary Developmental Biology”

IRI Life Sciences

Berlin, Germany

The Integrative Research Institute for the Life Sciences and Humboldt Universität zu Berlin invite applications for

2 Post-doctoral researcher (computational & wetlab) in the research group “Evolutionary Developmental Biology”

The junior research group headed by Dr. David Garfield focuses on understanding the regulatory mechanisms underlying embryonic development and how these mechanisms are shaped by evolutionary processes.
We are currently recruiting a computational post-doc and a wetlab-based Post-Doc for an ERC-funded project that uses single-cell sequencing (RNA and ATAC) to understand the evolution and function of the gene regulatory networks underlying sea urchin embryogenesis.

Research Projects:

Applicants for the computational part of the project would be involved in two specific sub-projects: i) the development of allele-specific methods for understanding the impact of regulatory mutations at single-cell resolution and ii) characterising trans-differentiation and cell-fate (re)specification following the removal, and subsequent recovery, of key embryonic cell lineages.

Applicants for the wetlab part of the project to would work on understanding the genetic bases of cell-fate specification and trans-differentiation in the development of the sea urchin larval skeleton. This project focuses primarily on developmental mechanisms, but interfaces closely with ongoing projects aimed at understanding how the gene network underlying sea urchin larval skeletogenesis evolves between species

Qualification and Experience

Eligible candidates for the computational-oriented position will have a PhD in computational biology, genomics, bioinformatics, or a related field along with strong quantitative/statistical skills. Previous experience with single-cell data is a desirable, but is not essential.

Eligible candidates for the wetlab-oriented position will have a PhD in developmental biology, genetics, or related fields with abackground in embryology (broadly construed). Research experience with sea urchins, Nematostella, or other marine models is a plus, but is not essential.

We offer a competitive salary (German E13 TV-L HU), with an initial contract of 2 years and the possibility of extension. The working language of the laboratory is English, and international applicants are most welcome.

The Garfield lab is based at the IRI Life Sciences, a collaboration between Humboldt University, the Charité Medical Centre, and the Max Delbrück Centre for Molecular Medicine. As members of the IRI, researchers have access to facilities and training opportunities at all three institutions located on a common campus in central Berlin, including computational resources associated with the Berlin Institute of Health.

Applications, including a motivation letter, CV, certificates and contact details for two academic references should be sent as a single PDF to info@garfieldlab.org. Applicants for the computational position should also provide example code, either by direct submission or via a link to GitHub or similar code repositories.
Applications will be considered until November 30th with an ideal start date in February 2019 (exact starting date is fairly flexible).

For more information, and to view the official job posting, please visit our website at
www.garfieldlab.org.

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Position

2 Post-doctoral researcher (computational & wetlab) in the research group “Evolutionary Developmental Biology”