14 PhD/Early Stage Researcher (ESR) positions offered by the consortium Training on Advanced Stem Cell Technologies in Neurology (ASCTN-Training, call H2020-MSCA-ITN-2018).

14 PhD/Early Stage Researcher (ESR) positions offered by the consortium Training on Advanced Stem Cell Technologies in Neurology (ASCTN-Training, call H2020-MSCA-ITN-2018).

ASCTN-Training consortium

Barcelona, Spain

ASCTN-Training is a four-year project, funded by the European Union Horizon 2020 Programme (H2020-MSCA-ITN-2018) under the Marie Skłodowska-Curie Initial Training Network and Grant Agreement No. 813851. ASCTN-Training is addressing existing gaps within Human Stem Cell-based Neuronal disorders (NDs) Modelling (NDM) for research to develop new medicines for the treatment of neurological disorders (e.g. Parkinson´s (PD), Huntington´s (HD) and Demyelination’s (DM) diseases), which occur as a result of acute or progressive loss of cells, glial or neuronal, and structures and function in the brain. ASCTN-Training sets out with the ambition to educate and train students within and across different scientific disciplines: biotechnology (Human Pluripotent Stem Cells (hPSCs) neuronal and glial differentiation using brain-on-chip technology and microfluidics, 3D tissue engineering/cerebral organoids and nanoengineering of culture conditions), molecular biology (Ex vivo gene expression, Direct cellular reprograming, mouse genetic modification, single cell analysis), in vivo mouse manipulations (Animal models of NDs, stem cell transplants into the brain, scaffold implantation, direct tissue engineering).

Available positions are:

ESR1
Principal investigator: Josep M Canals (jmcanals@ub.edu)
Host institution: University of Barcelona
Topic: Complex in vitro models for studying Huntington’s disease

ESR2
Principal investigators: Nick Allen and Anne Rosser (AllenND@cardiff.ac.uk; RosserAE@cardiff.ac.uk)
Host institution: Cardiff University
Topic: Modulatory functions of microglia on medium spiny neuron function and degeneration in stem cell models of Huntington’ Disease

ESR3
Principal investigator: Ernest Arenas (Ernest.Arenas@ki.se)
Host institution: Karolinska Institute
Topic: Dopaminergic differentiation brain-on-chip for Parkinson’s Disease

ESR4
Principal investigator: Vania Broccoli (broccoli.vania@hsr.it)
Host institution: San Raffaele Hospital
Topic: Efficient direct conversion of human somatic cells into induced dopaminergic neurons

ESR5
Principal investigator: Alberto Martínez (amserrano@cbm.csic.es)
Host institution: Autonomous University of Madrid
Topic: Improving reproducibility of cerebral organoid to study neurological disorders

ESR6
Principal investigator: Josep Samitier (jobs@ibecbarcelona.eu)
Host institution: Institute for Bioengineering of Catalonia
Topic: Brain-on-chip & 3D printing

ESR7
Principal investigator: Fabien Guillemot (fabien.guillemot@poietis.com)
Host institution: Poietis
Topic: 3D bioprinting for modeling and preclinical trials

ESR8
Principal investigator: Yen Choo (yen@plasticell.co.uk)
Host institution: Plasticell
Topic: Specification of striatal neurons using combinatorial cell culture technology

ESR9
Principal investigator: Federico Calegari (Federico.Calegari@tu-dresden.de)
Host institution: Technical University of Dresden
Topic: In vivo expansion of endogenous neural stem cells in a mouse model of stroke

ESR10
Principal investigator: Federico Calegari (Federico.Calegari@tu-dresden.de)
Host institution: Technical University of Dresden
Topic: Investigating the role of oligodendrocytes in in vivo models of demyelination

ESR11
Principal investigator: Josep M Canals (jmcanals@ub.edu)
Host institution: University of Barcelona
Topic: In vivo transplants of stem cells and artificial scaffolds to reconstitute brain tissues affected on Huntington’s Disease

ESR12
Principal investigator: Nick Allen and Anne Rosser (AllenND@cardiff.ac.uk; RosserAE@cardiff.ac.uk)
Host institution: Cardiff University
Topic: Understanding the connectivity of human striatal transplants in a rodent model of Huntington’s disease

ESR13
Principal investigator: Vania Broccoli (broccoli.vania@hsr.it)
Host institution: San Raffaele Hospital
Topic: In vivo direct conversion of glial cells into induced dopaminergic neurons.

ESR14
Principal investigator: Alberto Martínez (amserrano@cbm.csic.es)
Host institution: Autonomous University of Madrid
Topic: Improving integration and connectivity of dopaminergic neurons in vivo.

Requirements:
- A scientific university degree with exceptional academic performances
- Less than 4 years full time equivalent research experience and not yet been awarded a doctoral degree (PhD)
- Having resided less than 12 months in the country of application in the 3 years prior to selection
- Excellent communication and organization skills
- Fluent in spoken and written English
- Excellent writing and presentation skills
- Flexibility and ability to work in a team environment
- Availability to travel

Documentation to be sent to the Principal Investigator of choice:
- Cover letter describing your research career goals, skills and experience
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma (in English or with a translation into English)
- Two letters of recommendation

Length of appointment: 3 years

Application deadline: 15/12/2018

Starting date: 01/01/2019

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Position

14 PhD/Early Stage Researcher (ESR) positions offered by the consortium Training on Advanced Stem Cell Technologies in Neurology (ASCTN-Training, call H2020-MSCA-ITN-2018).