Post Doc Translational Genomics (f/m/diverse)

Helmholtz-Center München - German Research Center for Environmental Health - HMGU - Helmholtz Association

Neuherberg bei München, Bavaria, Germany

Work group:

Institute of Translational Genomics

Area of research:

Scientific / postdoctoral posts

Starting date:


Job description:

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.

The Institute of Translational Genomics focusses on translating insights from genomics into mechanisms of disease development and progression. At ITG, we leverage big data in genetics and genomics to gain insights into the mechanisms underpinning medically-relevant, complex human traits.

To join us on an exciting project applying knowledge gleaned from genomic studies in order to accelerate translation for common diseases of huge public health burden we are looking for a

Post Doc Translational Genomics (f/m/diverse)

Job Description
In this position you will take a leading scientific role in integrating signals arising from large-scale genome-wide studies (in >1M individuals) with deep multidimensional functional genomics data in order to map associated variants to likely causal genes. You will identify and validate novel treatment targets and opportunities for drug repositioning. You will use artificial intelligence approaches to stratify patients based on their genomic and molecular profiles, aiming to catalyse personalised medicine approaches and improve disease management. You will use causal inference analysis to disentangle the directionality of association across a range of disease risk factors. You will identify candidate biomarkers for validation, and will construct polygenic risk scores aiming to improve prediction and prognosis accuracy.

Your Qualifications
The ideal applicant will have expertise in applying computational approaches to the analysis of genomic datasets to infer translational insights. You will join a lively international group that combines expertise in genetics, statistics, computational biology, and bioinformatics in a friendly and collaborative environment.

Essential Skills
PhD in relevant discipline
- Experience in large-scale analysis of genomics data
- Programming skills (e.g. R, perl, python)
- Excellent communication skills, ability to develop good working relationships
- Good project management and organisational skills
- Attention to detail and ability to work to tight timelines
- English language well-written and fluently spoken
- Track record in producing publications

Our Offer
At the Helmholtz Zentrum München, you can contribute together with leading researchers to the investigation of the development, prevention and treatment of environmental diseases such as diabetes, chronic lung diseases and allergies. In order to further promote your professional development, we offer extensive and targeted research training and career programmes. We support the reconciliation between work and private life with flexible working time models, occupational health management, day care facility for children, a childcare subsidy, Elder Care, as well as other counseling and support services.

Remuneration and benefits are in accordance with the collective agreement for the public service (TV EntgO Bund).

The position is (initially) limited to three years.

The activity involves special knowledge and experience specific to own scientific skills.

As a holder of the Total E-Quality Award, we promote equality of opportunity. In order to increase the proportion of women in management positions, we would be pleased to receive corresponding applications. Qualified applicants with physical disabilities will be given preference.

We are looking forward to receiving your comprehensive online application until the 18th of November 2018.


Please apply via recruiter’s website.

Quote Reference: Helmholtz-2018/0482