Explore the biggest datasets on Alzheimer’s disease.
Predict molecules and molecular systems driving cognitive decline.
Test your predictions in preclinical validation experiments in our labs.
Uncover the foundation of Alzheimer’s disease, through integrated computation and experiments as a tenure-track Assistant Professor at the Rush Alzheimer’s Disease Center. This position offers unparalleled integration between data, experimental and pharmaceutical resources for combating Alzheimer’s. But don’t stop there – interact with neuropathologists, clinicians and other computational researchers to drive your solutions through to drug development, to create a major impact on the lives of individuals with Alzheimer’s.
What makes us different?
- We will rapidly test your predictions in our new genome editing lab and many affiliated labs
- Integrated perspectives on aging disease.
- Center is home to recognized experts on every aspect of Alzheimer’s.
- Possibility to work from anywhere – faculty on three continents in close communication.
- Our big data is the biggest – check it out (radc.rush.edu) You can utilize multi-omic data, all acquired in the same set of hundreds of individuals, including: histone acetylation, DNA methylation, ATAC seq, TMT proteomics, RNAseq (multiple brain regions) and single cell RNAseq. Clinical and pathological phenotyping: motor function, longitudinal cognitive tests, multi-modal neuroimaging, multi-region neuropathology, micro and macro infarcts, hippocampal sclerosis and TDP-43.
Develop and fund your research program in the general area of aging neurobiology and Alzheimer’s disease
PhD or MD/PhD with experience/publications in branches of computational biology
Experience with building computational pipelines
Experience with many aspects of processing omics data sets in systems biology
Preference for neurological disease experience
Preference for cloud computing and HPC experience
Preference for history of extramural funding
The Rush Alzheimer’s Disease Center is a world leader in research on Alzheimer’s Disease, with innovative approaches to understanding the molecular, clinical and social aspects of the disease, so that we can prevent it (publication link). Our 30 faculty and 130 staff are united in gathering molecular and clinical data on this disease, from thousands of participants in aging studies in the Chicago area and across the US. The Alzheimer’s Disease Center is part of Rush University, which is a large academic medical center, with associated Medical and Graduate Schools, in Chicago IL. For this position, location is flexible – you are free to work remotely from any location, as well as welcome in Chicago.
For pre-screening, compose a paragraph on why you are interested in this position, and attach your CV.
Applications evaluated on a rolling basis, and it is to your advantage to apply sooner.