As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.
Institute for Diabetes and Obesity
The Research Unit in Functional Genomics of Mitochondria, headed by Dr. Fabiana Perocchi, is looking for a highly talented and motivated computational biologist to join the Institute for Diabetes and Obesity (IDO) of the newly established Helmholtz Diabetes Center (HDC) in Munich (www.helmholtz-muenchen.de/hdc/index.html). We aim at reconstructing mitochondrial-signaling networks that generate in response to physiological and pathophysiological stimuli. Although a mitochondrial role in signal transduction has been suggested, it is still a mystery how the organelle senses, deciphers, and responds to intracellular and extracellular signals. To this goal, we combine systems biology approaches (genome-wide loss-of-function screens, proteomics, comparative genomics, and metabolomics) with traditional genetic, biochemical, and physiological techniques applied to yeast, mouse models, human cell lines and patient samples.
- Mining and integration of large-scale data derived from high-throughput genomics, proteomics and metabolomics analyses
- Data management including the development, maintenance, and support of associated biological software and databases
- Ability to work with experimental biologists and physicians
- Aid in the design of screening assays; The applicant is expected to provide bioinformatics input to experimental design and strategy and to have strong interpersonal skills
- MSc or PhD in mathematics, computer science, statistics, engineering, or a related discipline
- Strong programming skills with several statistical computing languages
- Significant familiarity with machine learning theory and statistical modeling algorithms
- Prior experience in mathematical modeling of biological networks, data mining and * integration is strongly desired
- Innovative and creative thinking
- Ability to work independently
- Outstanding written and oral English skills
At the Helmholtz Zentrum München, you can contribute together with leading researchers to the investigation of the development, prevention and treatment of environmental diseases such as diabetes, chronic lung diseases and allergies. In order to further promote your professional development, we offer extensive and targeted research training and career programmes. We support the reconciliation between work and private life with flexible working time models, occupational health management, day care facility for children, a childcare subsidy, Elder Care, as well as other counseling and support services.
Remuneration and benefits are in accordance with the collective agreement for the public service (TV EntgO Bund).
The position is initially limited to two years.
The activity involves special knowledge and experience specific to own scientific skills.
As a holder of the Total E-Quality Award, we promote equality of opportunity. In order to increase the proportion of women in management positions, we would be pleased to receive corresponding applications. Qualified applicants with physical disabilities will be given preference.
We are looking forward to receiving your comprehensive online application.
Dr. Fabiana Perocchi
Phone: +49 (0) 89 3187-3216
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute for Diabetes and Obesity
Ingolstädter Landstraße 1
85764 Neuherberg near Munich