The German Center for Neurodegenerative Diseases (DZNE) is a unique non-university research center which is dedicated to the subject dementia and all its areas, as well as other neurodegenerative diseases. The center compasses the full spectrum of fundamental research through population sciences to health care research. The DZNE stands for excellence in research and science management, translation of scientific results into practice, interdisciplinarity and internationalization. It is a research center within the Helmholtz Organization of German research centers. With over 1,000 employees from 55 nations, spread over 10 sites, the DZNE is one of the national and international leading research centers in its research field.
Flow Cytometry Specialist / Technical Assistant (f/m)
The Beyer lab is interested in elucidating the molecular mechanisms of immunoregulatory processes in T cells and myeloid cells and their influence on the development and progression of neurodegenerative diseases. The lab is using modern single-cell Omics technologies (RNA & epigenome) as well as multi-parameter flow cytometry to characterize the contribution of T cells and myeloid cells to neurodegeneration using genetically modified mouse models. The application of modern genome editing technologies (CRISPR/Cas9), both for transcriptional reprogramming of cells as well as generation of mouse models, is a further focus of the group.
The specialist will perform and oversee the following:
- New flow cytometric assay development including evaluation of new test systems, e.g. BD Symphony A5 and BD Symphony S6, performing method validation, and implementing new equipment, programs and/or procedures with a focus on multicolor applications (up to 50 colors) for neuro-/immunology and single-cell genomics
- Daily technical flow cytometric operations in a
Specimen processing, staining and reagents
Flow cytometry hardware/instruments
- Daily operation, quality control
- Resolving technical/instrumental issues including QC and compensation
- Analytic flow cytometric analysis
Generating preliminary reports
Assisting in training flow cytometry technologists in basic analysis procedures
- Writing technical policy and assay procedures in accordance with required regulatory, departmental, and institutional standards
- Re-evaluating methodology and making recommended changes
We are looking for individuals with a high motivation to work at the interface of immunology, neurosciences, and genomics on the forefront of health research. Experience with flow cytometry and flow cytometric cell sorting and fluency in English are required. A graduate degree (Bachelor or equivalent) in Natural Sciences or Engineering Science / a degree as technical assistant is considered a benefit. Further experience in immunology, single-cell technologies and genomics is preferred, but not essential. Flexible working hours are expected.
- An interesting and challenging task in a research center that works on the future topics of health research.
- An international environment characterized by a strong focus on science and research.
- A high potential for the individual development of our employees.
- Targeted personnel development.
- A full-time position, initially temporary limited to 2 years.
- Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD Bund).
The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply.
Please apply via: