The Centre of Ophthalmology, Tuebingen is a Centre of Excellence in Germany, housing multiple scientific teams who work together to analyze genetic variation, relevant pathways and mechanisms of eye diseases. There are >400 employees who recently moved into a new state-of-the-art facility. The Centre of Ophthalmology is embedded in an excellent, internationally competitive research environment and the greater community at University of Tuebingen with its Excellence Cluster in Neuroscience linking up to other top research units (Max Plank Institutes, Hertie Institute of Brain Research etc.) in close proximity.
The Fischer Lab of the Centre of Ophthalmology (http://www.eye-tuebingen.de/fischerlab/) is inviting applications for a
1. FUNDED PHD POSITION (M/F)
2. FUNDED POSTDOCTORAL RESEARCH POSITION (M/F)
Fixed term for 3 years
Project title: Innate immune responses following adeno-associated virus mediated gene therapy
Head and PI: Prof. Dominik Fischer
A multidisciplinary project exploiting both immunology and ophthalmology to explore innate immune responses following Adeno-Associated Virus (AAV) gene therapy administration in the retina. We seek a creative and enthusiastic PhD student to work on our following research goals: identification of key recognition pathways of innate immunity detecting AAV and elaboration of strategies to prevent immune responses following AAV gene therapy. The candidate will be enrolled into the PhD Graduate Program of the Medical Faculty of University of Tuebingen https://bit.ly/2oZqCnP
Start of project: 01 December, 2018.
Salary: PhD position: 50% TV-L E13 (collective wage agreement for the Public Service of the German Federal States).
Postdoctoral position: 50-85% TV-L E13.
Application deadline: 01 November 2018. The receipt of the applications after deadline is possible if appropriate candidate is not found.
Entry date: as soon as possible. Review of applications will begin immediately and continue until the position is filled.
Profile of candidate’s qualification for PhD position:
Applicants must have (or expect to obtain) a Diploma/Master's degree in immunology/biology discipline that is relevant to the project. Ideally, the candidate will have a strong background in innate immunity. Motivation, creativity and intellectual independence are desirable as are excellent communication skills with the ability to work collaboratively. Previous experience in working with cell culture and molecular biology techniques would be an advantage. Fluency in English is indispensable.
Profile of candidate’s qualification for postdoctoral research position:
Applicants must have (or expect to obtain) a PhD degree in immunology that is relevant to the project. Ideally, the candidate will have a strong background in innate immunity. Motivation, creativity and intellectual independence are desirable as are excellent communication skills with the ability to work collaboratively. Previous experience in working with cell culture and molecular biology techniques would be an advantage. Fluency in English is indispensable.
Methods that will be used:
• Molecular biology
• Fluorescence microscopy
• Cell culture based methods
• FACS, RNA expression analysis, ELISA
• AAV production
Applications should include a motivation letter, CV with a list of publications, a copy of academic transcripts and the contact details for at least two academic referees, and should be sent by email to Dr. Dauletbekov (email: firstname.lastname@example.org), including “PhD Innate immunity to AAV” or “Postdoc Innate immunity to AAV” in the subject line. The cover letter should explain why you wish to be considered for the position and describe the qualities and experience you will bring to the role.
For further information please contact:
University Eye Clinic Tuebingen
Dr Daniyar Dauletbekov
Elfriede-Aulhorn Str. 7
Phone: (+ 49) 7071 29 87894