Research Fellow (Cellular Immunology, SIgN) A*STAR

Research Fellow (Cellular Immunology, SIgN) A*STAR

A*STAR Research Entities

Singapore, Singapore

Research Fellow (Cellular Immunology, SIgN) A*STAR

An initiative of the Biomedical Research Council (BMRC) of the Agency for Science, Technology & Research (A*STAR), the Singapore Immunology Network (SIgN) has setup its premise at the Biopolis, Immunos building (6000sqmt and ~150-200 researchers). SIgN aims to build up a strong program in immunology research in order to improve global understanding of the human immune system, and the translation of this knowledge into medical applications. Learn more about SIgN at

A Postdoctoral Research Fellow position is immediately available at SIgN. The over all interest of the lab is to carry fundamental and translational research, to investigate the molecular mechanisms and signaling pathways that contribute to the reprograming of host immuno-metabolic circuits during Mycobacterium (and Gram negative bacteria) infection. We utilize animal models, patient derived materials and advanced immunomics approaches to identify the key host-factors regulated during infection, and which can be targeted to develop host-directed preventive and therapeutic approaches. For details refer to following articles:

Singhal et al. Metformin as adjunct anti-tuberculosis therapy. Sci Transl Med. 2014. Nov 19;6(263):263ra159.
Cheng et al., Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis. Sci Immunol. 2017 Mar;2(9). pii: eaaj1789.

Candidates should have demonstrated significant scientific accomplishment at the graduate or postdoctoral level with a solid background in cellular immunology and/or molecular & cellular biology. Working experience with animal models and technical competency of fluorescence / confocal microscopy and flow cytometry is required. Knowledge of infectious diseases is important but not essential. The successful candidate should be able to design and execute experiments, analyze and interpret data, write manuscripts for publication and present data to both national and international audiences. 1-2 year post-doctoral experience is preferred.

Job Requirements:
• A doctoral degree in cellular and molecular immunology, life sciences or related fields
• Team player, independent, self-driven with good interpersonal skills
• Good knowledge of cellular biology, immunology and infectious diseases; and
• Strong communication and excellent writing skills

Interested applicants should send a copy of their resume with publication list, one page of summary of research experience and interests, and contact information of three referees who could be contacted for letters of reference to Dr. Amit Singhal at

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice.

We regret that only shortlisted candidates will be notified.


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Research Fellow (Cellular Immunology, SIgN) A*STAR