POST-DOCTORAL & RESEARCH ASSOCIATE POSITIONS:
DEFINING THE ROLE OF HMGA CHROMATIN REMODELING
PROTEINS IN NORMAL STEM CELL & CANCER BIOLOGY
We are seeking highly motivated and enthusiastic postdoctoral fellows and experienced research associates to join the research laboratory of Dr. Linda Resar. Our laboratory is currently funded by 3 NIH R01s, Maryland Stem Cell Research Funds, and private foundations to study High Mobility Group A proteins in cancer, cancer stem cells, and normal development.
The Resar laboratory is located in the Ross Research Building of the Johns Hopkins University School of Medicine in Baltimore, Maryland, with outstanding core facilities and equipment.
This position requires a PhD and/or MD in a relevant area with a strong interest in stem cell and cancer biology. Previous experience in molecular biology, tissue culture, and intestinal and/or hematologic stem cell biology are highly desirable. Innate curiosity, drive, and the ability to work as a team are essential for this position.
1) Biology of intestinal and colon stem cells & gastrointestinal cancer
2) Pediatric leukemia (bioinformatics expertise helpful)
3) Hematologic malignancy and stem cell biology
4) Aging biology using mouse and cell-based models
Please send a cover letter, curriculum vitae, and forward 3 letters of reference to: firstname.lastname@example.org
Xu Y, Sumter Felder T, Bhattacharya R, Tesfaye A, Wood, LJ, Fuchs E, Huso D, Resar LMS. The HMG-I oncogene causes highly penetrant, metastatic lymphoid malignancy in transgenic mice and is overexpressed in human lymphoid malignancy. Cancer Res 2004;64:3371-5. Published as a Priority Report
Xian L, Georgess D, Huso T, Cope LM, Belton A, Chang Y-T, Kuang W, Gu Q, Zhang X, Senger S, Fasano A, Huso DL, Ewald AJ, Resar LMS. Hmga1 amplifies Wnt Signaling and expands the intestinal stem cell compartment and Paneth cell niche. Nature Commun 2017;8:5008. Cited as paper of significance (Intestinal Cell News; Issue 3.15)
Resar LMS, Chia L, Xian L. Lessons from the crypts: HMGA1 – amping up Wnt for stem cells and tumor progression. Cancer Res 2018;78:1890-97….