PhD Student/Postdoc in the Field of Infection and Cancer Immunology

PhD Student/Postdoc in the Field of Infection and Cancer Immunology

Heinrich-Heine University (HHU) - University Hospital (UKD)

Düsseldorf, Germany

We are looking for a highly motivated Master/PhD Student or Postdoctoral Fellow, who is interested to work in the field of infection and cancer immunology. In particular, the innate and adaptive immune system will be analyzed by investigating viral infections and cancer models in an in vivo and in vitro system. The aim is to understand the development of chronic viral infections and cancer progression and develop therapeutic strategies with basic research techniques. The models will focus on murine viruses such as the lymphocytic choriomeningitis virus and cancer models. Please send a CV and a list of publication to: molmed2@uni-duesseldorf.de

Methods:
- Tissue culture
- RT-PCR
- PCR
- Virus Handling and virus techniques
- Flow Cytometry

Please refer to:

Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS. Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression. Nat Commun. 2017 Mar 1;8:14447.

Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, Mak TW, Ohashi PS, Lang KS, Lang PA. Type I interferon protects antiviral CD8 T cells from NK cell cytotoxicity. Immunity. 2014 Jun 19;40(6):949-60.
Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, Hengel H, Pfeffer K, Tanaka M, Häussinger D, Recher M, Lang PA, Lang KS. Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nat Immunol. 2011 Nov 20;13(1):51-7.

Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, Hegazy AN, Lohning M, Harris NL, Ohashi PS, Hengartner H, Zinkernagel RM & Lang KS. Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med 2008; 14:756-761


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Position

PhD Student/Postdoc in the Field of Infection and Cancer Immunology