Postdoctoral Fellowship Position in Innate Immunity and Neurodegeneration
Postdoctoral position is available immediately in the laboratory of Towfique Raj PhD, at Icahn School of Medicine at Mount Sinai in New York City, for outstanding, highly motivated postdoctoral research fellows to play a major role on projects to study molecular mechanisms of neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. This is a great opportunity for a self-motivated, innovative and organized candidate with excellent communication skills to work in a dynamic laboratory undertaking cutting edge research.
The successful candidate will develop an independent research project to study the role of primary myeloid cells (peripheral monocytes/macrophages and CNS microglia) in neurodegeneration. The candidate will have access to human biological, clinical, and genetics data from Alzheimer’s and Parkinson’s disease patients. An ongoing effort is to employ a human cell-based culture system to validate PD and AD candidate genes identified from our integrative genomics study, and ultimately to bridge the gap between systems biology and disease mechanisms. One of the project focuses on the function and phenotype of the innate immune cell populations following perturbation of immune homeostasis. Key to the success of the project will be integration of quantitative ‘omics data (single cell RNA-seq, CyTOF, and proteomics) with phenotypic data.
Highly motivated, recent PhD graduates with experience and publications in the fields of neuroscience, cell biology, molecular biology, biochemistry, and/or genetics are encouraged to apply. Experience with cell sorting, FACS / flow cytometry techniques. Experience with experimental techniques for myeloid phagocytosis, lysosomal biology and autophagy will be a plus. Experience with genomics/transcriptome data analysis is highly desired. Ability to work and communicate effectively in an interdisciplinary work environment. An interest in working with a diverse group of scientists to advance understanding of neurodegenerative diseases through a synergy of wet and dry lab approaches.
To apply, please send a full CV, a brief statement of current research and long-term goal, and names and contact information of three references to Dr. Towfique Raj at firstname.lastname@example.org.
The Raj Laboratory is a member of the Ronald M. Loeb Center for Alzheimer's Disease (http://icahn.mssm.edu/research/loeb-alzheimers), Departments of Neuroscience, Genetics, and Genomic Sciences, Institute for Genomics and Multiscale Biology, and Friedman Brain Institute at Icahn School of Medicine at Mount Sinai in New York City. More info: http://neuroscience.mssm.edu/raj/. …