Postdoctoral Researcher in T Cell Biology

Postdoctoral Researcher in T Cell Biology

Washington University School of Medicine

Saint Louis, United States

Postdoctoral positions for projects examining T cell responses to viral infection, cancers and microbiota at Washington University School of Medicine

We are seeking for 2-3 postdoctoral fellows to study T cell immune responses to pathogens, cancers and intestinal microbiota. The goals are to understand cell intrinsic programs by which T lymphocytes differentiate into effector, memory or regulatory cells, and define the impact of these programs on antiviral host protection, control of tumor growth and establishment tolerance at host-microbiota interface. We are conducting collaborative research between the three labs of Takeshi Egawa (antiviral, anti-tumor T cell responses), Chyi-song Hsieh (Treg induction in response to microbiota) and Haina Shin (antiviral responses at mucosal tissues) with complementary expertise in T cell biology. We will use animal models (viral infection, tumor models, germ-free mice), genetic and epigenetic profiling, and the generation of genetically modified mice to address these questions.
Strong candidates are expected to have experience in mouse studies, flow cytometry, and molecular and cellular biology. Additional expertise in bioinformatics, epigenetic analyses and culture of microbes is preferred. The positions will be in either the Department of Pathology and Immunology or Department of Medicine at Washington University School of Medicine, located in Saint Louis, MO, USA. Washington University is a scientifically rich environment offering close interactions with leading immunologists and microbiologists as well as state-of-art core facilities, which will foster the development of a successful research career.

Selected Recent Publication:
Raju S. et al., PLoS Pathog. 2018;14:e1007053, PMID: 29734372
Chou, C. et al., Immunity, 2016; 45:570-582. PMID: 27566940
Ebihara, T. et al., Nat Immunol. 2015;16:1124-1133. PMID: 26414766
Chou, C. et al., Nat Immunol. 2014;15:884-893. PMID: 25029552

Perry, JSA., et al., Immunity, 2018;48:923-936. PMID: 29752065
Chai, JN. et al., Sci Immunol., 2017;2(13). PMID: 28733471
Nutsch K. et al., Cell Rep., 2016;17:206-220. PMID: 27681432
Perry, JSA., Lio CJ. et al., Immunity, 2014;41:414-426. PMID: 25220213
Lathrop et al., Nature, 2011;478:250-254. PMID: 21937990

Scott, JM. et al., J Virol. 2018; pii: JVI.00038-18. PMID: 29343577
Shin H., Curr Opin Virol. 2018;28:61-67. PMID: 29175730
Shin H., et al., Nat Commun. 2016;7:13346. PMID: 27827367
Shin H. and Iwasaki, A., Nature. 2012;491:463-7. PMID: 23075848

Please send your CV, a brief statement of your past accomplishment and prospective goal (1-2 pages each), and email addresses of two or more references to:

Takeshi Egawa
Department of Pathology and Immunology
Washington Universtity School of Medicine

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Postdoctoral Researcher in T Cell Biology