Within the Technology and CMC Development Department, you will integrate a team of 40 people whose mission is to design innovative technologies, develop them as GMP-compatible production processes and characterize them according to the regulatory requirements for phase I / II clinical trials. Upstream of this activity, you will supervise a team of 2 engineers and 3 technicians dedicated to innovation and design of AAV vector expression systems.
Your main missions are:
- To develop innovative strategies to produce recombinant AAVs in different cellular systems,
- To collaborate with bioprocess development teams to integrate these new technologies into manufacturing processes related to preclinical / clinical projects,
- To collaborate with research teams to integrate early strategic directions in terms of new therapeutic vectors.
PhD in molecular and / or cellular biology, you are familiar with molecular virology techniques (preferably applied to AAV): platform of stable and / or transient expression in mammalian and / or insect cells.
You have 5 to 10 years of experience and a solid expertise in the field of viral vectors applied to Gene Therapy.
You are skilled in writing protocols, reports and scientific publications. Knowledge of Vector NTI / SnapGene software or equivalent and MS Office is required.
English imperative and French desired.
Good communication skills, team spirit, capacity of being critical, rigorous, autonomous, enthusiastic, are qualities that will allow you to succeed in this position.
Permanent position, based in Evry (91), to be filled as soon as possible.
To apply, please send your CV and cover letter by email to Sabine DAVID, HR Department: email@example.com…