Postdoctoral Research Associate in Structural Biology

University of Oxford

Oxford, United Kingdom

Salary: Grade 7: £31,604 - £38,833 p.a.

We are seeking to appoint a Postdoctoral Research Associate to join the team of Professor Elena Seiradake. The Seiradake group combines structural biology with cell biology and neurobiology, providing access to expertise and training in these areas. The successful candidate will aim to reveal the structures, biophysical properties and functions of adhesion G-protein-coupled receptors (GPCRs) and their ligands in the nervous and vascular systems. The work will be focused on the soluble extracellular regions of the receptors using X-ray crystallography and trans-membrane constructs using cryo-electron microscopy. The planned research includes protein expression using insect or mammalian cells, protein purification and biophysical analysis, and structural analysis using X-ray crystallography and cryo-electron microscopy. The project also involves collaboration with teams at Oxford and overseas.


Applicants should possess a PhD/DPhil, or be near completion of a PhD/DPhil, involving structural biology, and have excellent relevant skills in protein purification and either X-ray crystallography or electron microscopy. A good publication record (taking the career stage into account) is expected. Applicants should be well-trained, enthusiastic and self-motivated, with excellent team-working and interpersonal skills. You should also have excellent communication skills. The successful candidate may be required to travel overseas to conduct collaborative experiments as and when necessary to advance the research project. Applicants with experience in expressing and purifying proteins for structural analysis from insect or mammalian cells would be especially welcome. Specific expertise in cryo-electron microscopy and/or cross-linking mass spectrometry would also be advantageous.


This full-time fixed-term post is funded by the UK's Wellcome Trust for up to 2 years in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford.


The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available. Further particulars, including details of how to apply, can be obtained from the document below.


The closing date for applications is 12.00 noon on Wednesday 23 May 2018, with interviews for shortlisted candidates to be held on as soon as possible thereafter.

Please apply via recruiter’s website.

Quote Reference: University of Oxford-itox_ac-134616