Astex Pharmaceuticals Limited

X-ray Crystallography Software Developer (Ref: XS/0519)

Astex Pharmaceuticals Limited

Cambridge, United Kingdom

Job Description: X-ray Crystallography Software Developer (Ref: XS/0519)

Job Type: Permanent

Location: Cambridge, UK

Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary fragment-based drug discovery platform to generate multiple new drug candidates that are progressing in clinical development. Astex continues to grow and focus on oncology and neurological disorders.



Astex has a strong culture of developing bespoke software to support our fragment-based drug discovery platform and in particular our high throughput X-ray crystallography pipeline. As part of Astex’s ongoing commitment to extending its existing computational crystallography infrastructure, the Molecular Sciences Group has an opportunity for a highly motivated scientist to join the X-ray Technology Team. The ideal candidate will be a crystallographer with an aptitude for software development, or a computer scientist with experience of working in macromolecular crystallography.

Principal Responsibilities:

  • Design and implement computational crystallography tools and web applications
  • Maintain and improve the existing computational crystallography platform
  • Keep abreast of the latest developments in crystallography to identify new opportunities
  • Collaborate with and work alongside structural biologists and software developers at Astex

Skills and Experience Required:

  • Degree in physics, chemistry, biology, computer science or related field
  • Background in crystallographic computing
  • Proven software development experience working in industry or an equivalent academic setting
  • Expert knowledge in Python and/or JavaScript
  • Knowledge of Perl, C++, Fortran and experience with relational databases is a plus
  • Familiarity with common software development tools and practices (version control, testing, etc.)
  • Excellent team working, written and verbal communication skills

We offer excellent training and career development opportunities as well as a highly competitive salary and benefits package.

Closing date: 31st January 2020

To apply, please send your CV and a cover letter quoting the job reference: XS/0519 to



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X-ray Crystallography Software Developer (Ref: XS/0519)