The Francis Crick Institute

Translational Project Research Scientist - Developmental Signalling Lab

The Francis Crick Institute

London, United Kingdom

Job title: Translational Project Research Scientist – Developmental Signalling Lab

Location: The Francis Crick Institute, Midland Road, London

Contract: Fixed-term (1 year), Full time.

Salary: Competitive with benefits, subject to skills and experience

Vacancy ID: 12247


An exciting opportunity to work on a translational project, developing a potential therapeutic for pancreatic cancer – one of the hardest to treat tumours.

We seek a talented and motivated Project Research Scientist (post PhD) with expertise in mouse models of cancer to join Dr Caroline Hill’s Developmental Signalling Laboratory at the Francis Crick Institute. The project will involve testing a potential therapeutic that we have generated, in mouse models of pancreatic, and also breast, cancer. It will also involve analysis of human samples. The project is a collaboration between an academic lab at the Francis Crick Institute and a large pharmaceutical company and will appeal to someone with a PhD and relevant expertise in mouse cancer models who is interested in pursuing Translational research.

The successful applicant will be a highly creative and motivated individual, able to work independently and also capable of interacting well within a group, keeping detailed records of experiments, and communicating well.

Project scope

The project is a proof-of-principle Translational project that will be based in the Developmental Signalling lab directed by Dr Caroline Hill. Her lab is focused on understanding how TGF-b superfamily signalling pathways function normally in early vertebrate development and in adult untransformed tissue culture cells, and how these signalling pathways are perturbed in disease, in particular, cancer. The group currently comprises nine people – five postdocs, three PhD students, and a principal laboratory research scientist. Four of the lab members focus primarily on working on these signalling pathways in the context of zebrafish development, whilst the others focus on the disease aspects of signalling. This project will involve collaborations within the lab, with other groups at the Crick and also with a large pharmaceutical company.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

  • If you are interested in applying for this role, please apply via our website.
  • The closing date for applications is 27 October 2019 at 23:45.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

Please apply via recruiter’s website.