National Institutes of Health

Staff Scientist--Genomic Pathology

National Cancer Institute, Laboratory of Pathology

Bethesda, MD, United States

The mission of the Laboratory of Pathology is to achieve the highest level of quality in diagnostics, education and research. LP takes on the responsibility for all anatomic pathology services for the NIH, as well as accepted cases from national and international healthcare organizations seeking our expertise through consultation. By continuing to expand the scope of our expertise and by incorporating the newest tools of diagnosis, training, and research, the LP goal is to be a globally recognized center of excellence for clinical diagnostics, disease research, and pathology education.

This position is in the Genomic Pathology Section (Kenneth Aldape, Chief) of the Laboratory of Pathology, Center for Cancer Research, National Cancer Institute. The section focuses on the bulk and single-cell cancer genomic signatures that can improve our understanding and classification of cancer. We are particularly interested in the integration of epigenomic with transcriptomic signatures on the single-cell level. The incumbent is a highly proficient professional researcher who is adept at number of informatics tools, but also who possess deep knowledge and interest in cancer genomics. The individual should be proficient in written and spoken English, is capable of high levels of service and production of work, and will be responsible for examination of genomic signatures in human cancer specimens, including informatics analyses of high-throughput next generation sequencing data and single-cell sequencing, including single-cell methylation. The incumbent will be assigned responsibility to independently investigate problems and develop techniques and procedures that are recognized as being difficult to solve and require the sophistication, creativity and judgement. Projects will focus on the use of genomics and epigenomics to better understand human cancers and cancer subclasses. This exceptional opportunity offers the chance to work at the forefront of cancer genomic discovery and translational cancer technologies and applications.   Utility in TCGA and other big genomic data sources is a must. The NCI is a rich environment with a wealth of biological and computational resources dedicated to the study of cancer genomics.

RESPONSIBILITIES AND REQUIREMENTS

  •  PhD or MD or both with experience in cancer biology, bioinformatics, statistics, physics or any other field with relevance to biology/computational biology
  • Proficiency in basic programming fundamentals for data analysis (preferably in R and in one of the scripting languages such as Perl/Python)
  • Ability to collaborate and communicate complex technical concepts
  • Understanding of basic cancer molecular biology principles is highly preferred
  • Send an introductory email titled “Staff Scientist Position – (your name)” to kenneth.aldape@nih.gov with a CV and one-page research statement addressed to Dr. on or before April 30, 2019, or until filled.
  • Examines genomic signatures in human cancer specimens, including informatics analyses of high-throughput next generation sequencing data and single-cell sequencing, including single-cell methylation
  • Skills in writing editing and reviewing technical and scientific communications and documents, and ability to communicate (oral and written) effectively with multidisciplinary teams
  • A record of peer-reviewed publications required


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Position

Staff Scientist--Genomic Pathology