The Angelo Lab is looking for a staff scientist to join our team. We are an interdisciplinary group focused on understanding how the immune system contributes to human disease. Our lab environment is extremely collaborative, and we have projects across a wide range of subject areas.
We are looking for someone to manage and execute collaborative projects with industry and academic partners. The ideal candidate will be able to independently manage complex scientific projects, design and execute experimental plans, and communicate results effectively to collaborators across a range of disciplines and backgrounds. The candidate will play a significant role in the design and execution of experiments, as well as interpretation of results. In addition, the candidate will be responsible for communicating with collaborators, including summarization and analysis of data.
The projects will involve application of our novel imaging technology, Multiplexed Ion Beam Imaging by Time of Flight (MIBI-TOF). The applicant will gain significant expertise is the usage and operation of this mass-spectrometry based imaging platform. Routine duties will include optimization of reagents, validation of correct staining, and operation of the instrument to profile large cohorts of clinical samples across a range of pathologies, including cancer, infection, and auto-immunity.
Qualified candidates will have a PhD in a relevant field, such as immunology, biology, or genetics. Qualified candidates will also have an excellent track-record of organizational skills, project management abilities, and be able to work well as part of a team. Exceptional candidates will have previous experience with imaging analysis, such as immunohistochemistry or immunofluorescence.
MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure. Keren, Bosse et al., Science Advances (2019).
A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging. Keren et al., Cell (2018)
Multiplexed ion beam imaging of human breast tumors. Angelo et al., Nature Medicine (2014)