Novo Nordisk Research Centre Oxford (NNRCO)

Specialist statistical genetics - Clinician scientist

Novo Nordisk Research Centre Oxford (NNRCO)

Oxford, United Kingdom

Do you have insights into the clinical aspects of cardiometabolic diseases? And are you motivated by the prospect of leading projects to identify drug targets using genetics data? Then this could be your opportunity to take the next step in your professional journey and join an ambitious Genetics department at Novo Nordisk Research Centre Oxford.

About Novo Nordisk Research Centre Oxford (NNRCO) NNRCO is our new translational research institute focused on target discovery across the broad spectrum of cardiometabolic disease. We aim to combine the very best of academia, biotech and big pharma, fusing a deep understanding of human genetics, an agile, creative and collaborative culture and drug development. NNRCO will be a world-leading research site focused on asking the big and difficult questions and delivering high impact science.

You can read more about NNRCO at:

About the department You will be part of our Department of Genetics led by Sr. Director, Joanna Howson PhD. The department is expanding, and will consist of Specialists, Research Scientists, and Postdocs. Currently, we are 5 people who share a passion for genetics and drug discovery. The focus of this Department is to use data science and human genetics to identify new drug targets, through a range of approaches e.g. high-throughput genetic discovery screens; Mendelian Randomization; pLoF variant screens and precision medicine approaches relevant to type 2 diabetes, non-alcoholic steatohepatitis (NASH) and other cardiometabolic traits.

The position As a Specialist, you would be responsible for conceiving and leading projects to identify drug targets for Cardiometabolic diseases using genetics (e.g. post GWAS methodologies).

To succeed in this, it will be key that you establish collaborations and partnerships with universities and relevant businesses/biotech companies. Collaboration is an established part of our working culture and we believe that we have the biological and technological expertise to be a world class collaboration partner. Within the NNRCO, you will work closely with other statistical geneticists and computational biologists, cell biologists and laboratory scientists.

Furthermore, you would be expected to provide expertise in clinical aspects of one or more cardiometabolic diseases (e.g. coronary diseases and renal diseases), and on methodologies and analyses of genetics data (e.g. GWAS, ’omics integration, interpretation of results from genetic data analyses).

Being a specialist, you would also be acting as a role model for more junior colleagues, and it would be an important part of your role to take responsibility for passing on your knowledge and supporting more junior members of the department in their work.

Qualifications In this position it is required that you have a MD and PhDin a relevant field e.g. statistical genetics, genetic epidemiology, clinical science or related along with significant relevant experience post PhD. In addition, you have some experience working in a clinical setting with cardiometabolic diseases e.g. renal, cardiovascular or diabetes. It would be considered an advantage if you have experience in Mendelian randomisation.

You will be expected to work well both independently designing and driving the direction of projects, as well as collaboratively as part of a team alongside other inter-disciplinary colleagues in the project team, across NNRCO departments and with external collaborators. You show a positive “can-do” attitude, are flexible, open to new ideas and are results oriented. The job requires proficiency in English and excellent communication and collaboration skills.

Working at Novo Nordisk At Novo Nordisk, we use our skills, dedication and ambition to help people with diabetes. We offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.

Contact For more information, please contact recruitment partner Nana Nielsen at (+45)30776105 or Jo Howson by email:

Deadline 16 August 2020

Please apply via recruiter’s website.

Quote Reference: 57241