Cancer Research UK (CRUK)

Senior Software Architect

Cancer Research UK (CRUK)

Manchester, United Kingdom

Senior Software Architect

  • Salary in the range of £28,000 – £36,000 per annum (dependent upon experience)
  • Job Ref: MI/19/23
  • Duration: Permanent

About the role:

The Cancer Research UK Manchester Institute (CRUK MI) has access to state of the art genomics, proteomics and imaging technology, which are together being used to advance our understanding of cancer. Our aim is to gain a greater understanding of the fundamental basis of how cancer develops and apply that knowledge to develop new diagnostic tests, potential treatments and better ways to predict the outcomes. Genomics technologies are central to this work, and analysis of the data generated by these technologies is reliant on substantial amounts of computing. Among others this is achieved on site through the use of a dedicated HPC facility housed in a machine room on site.

We are seeking a Senior Software Architect to join our dynamic Scientific Computing Team. You will support users in developing, maintaining and running bioinformatic analysis pipelines to support the processing of large volumes of deep sequencing and protein mass spectrometry data. Pipelines will run on a 1,500 core HPC cluster that resides in a dedicated data centre on site. The Scientific Computing team provides a stimulating and motivating work environment. You will be encouraged and supported to keep track in this rapidly developing field.

About you:

You will have a degree in Computational Biology, Mathematics (or related discipline) plus significant relevant experience or a postgraduate degree in a related discipline. You will have excellent programming skills, a familiarity with collaborative coding in an HPC environment and strong communication skills. You will relish the prospect of joining a highly interdisciplinary team that combines biology with computer science, mathematics and software engineering, whose goal is to help understanding the cancer genome.

Although an understanding of cancer genomics and cell biology would be advantageous, it is not a prerequisite, and accomplished developers with a proven ability to learn new problem domains are encouraged to apply.

Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

We are partnered with The Christie NHS Foundation Trust in South Manchester (, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

How to apply?

To apply for this position please visit our website:

For any informal enquiries about this post, please contact Dr Marek Dynowski, Head of Scientific Computing, via email:

Closing date: 07 July 2019.

Please apply via recruiter’s website.