Senior Research Scientist Computational Chemistry – 2-year position with the possibility of a permanent position
Lundbeck is a global pharmaceutical company with approximately 5,000 employees across 55 countries specialized in psychiatric and neurological disorders. At Lundbeck we are highly committed to improving the quality of life of people living with brain disease. The Computational Chemistry department is part of the Division of Molecular Discovery and Innovation within Lundbeck Research. The department currently consists of 4 scientists and is based at Lundbeck’s headquarters in Valby, Copenhagen.
The Computational Chemistry department is responsible for all Computational Chemistry/Computer-Assisted Drug Design (CADD), and Structural Biology efforts in Lundbeck Research. We are fully integrated into the discovery process, working with scientists from multiple disciplines from the earliest stage of target validation through hit/lead identification to optimization of compounds for clinical development. Some of our key responsibilities are to support the chemistry and biologics programs with structural understanding, idea generation, and predictive modelling using rational design. The group is continuously looking into new technologies, and now we are in the process of building an Artificial Intelligence platform for Medicinal Chemistry. We work closely together in an informal team atmosphere. We are now looking for a new team member.
Your job and key responsibilities
Your main responsibilities will be to provide Computational Chemistry input into the drug discovery programs. To impact the success of these you will be directly involved in the drug discovery project teams, where you will proactively use cutting-edge Computational Chemistry and other in silico and data mining approaches. You will use both ligand- and structure-based methods to prioritize and design compound ideas. You will also be responsible for effective delivery of tasks to foster project progression, as well as to lead or contribute to other initiatives for the enhancement of Lundbeck’s drug discovery efforts. You will be working as a keen team player, and be able to operate independently in an effective, motivated and highly communicative way.
Now you have the opportunity to join a team of highly qualified colleagues, where you will have excellent possibilities for scientific and personal development.
You are an enthusiastic and motivated scientist with comprehensive experience in Computational Chemistry/Computer-Aided Drug Design (CADD), with the following profile:
- PhD in a relevant subject with 2-3 years of post PhD experience, preferably in a pharmaceutical company
- thorough knowledge and experience in structure- and ligand-based drug design, SAR analysis, chemistry, and how structural changes will affect ligand binding as well as druggability.
- skills in the field of informatics and data analytics, including AI applied to Medicinal Chemistry would be a benefit.
- enjoy and are effective at being a team player, including 2-way communication, with a can-do attitude.
- skilled at working with medicinal chemists in hypothesis generation.
fluent in written and oral English.
Applications must be received no later than May 28th 2020 and should include a cover letter with curriculum vitae as well as the names and contact details for two referees. We will conduct interviews as we receive applications.