Astex Pharmaceuticals Limited

Scientific Software Developer

Astex Pharmaceuticals

Cambridge, United Kingdom

Job Title: Scientific Software Developer (Ref SD/1119)

Job Type: Full Time

Location: Cambridge, UK

Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery platform to generate multiple new drug candidates that are progressing in clinical development. Successful collaborations have led to two launched oncology drugs (Kisqali® partnered with Novartis and BalversaTM partnered with Janssen). Astex continues to grow and focuses on Oncology and Neurological Disorders.

Astex have a strong culture of developing bespoke software to support our fragment-based drug discovery platform. The role offers a range of opportunities to develop scientific software in the structure-based drug design (SBDD) and cheminformatics areas, using state-of-the art technologies including the application of modern machine learning methods. The ideal candidate will be a computational chemist or biologist with an aptitude for software development, or a computer scientist with experience of working in a chemistry and/or structural biology related discipline. The applicant will have a keen interest in developing web applications.

Principal Responsibilities

• Design and develop bespoke SBDD and cheminformatics web applications
• Keep abreast of the latest technologies to identify new opportunities
• Promote close interactions across multidisciplinary groups
• Collaborate with scientists throughout the company to develop cutting edge software tools
• Provide informatics support for drug discovery programs

Preferred Skills and Experience Profile

• Degree in chemistry, biology, computer science or related field
• Proven software development experience working in industry or an equivalent academic setting
• Excellent team working, written and verbal communication skills
• Expert knowledge in Python
• The following additional expertise/skills would be beneficial
o Experience in Perl, Java, C/C++, Javascript
o Experience with relational databases e.g. Oracle, MySQL
o Experience with full stack web development

We offer excellent training and career development opportunities as well as a highly competitive salary and benefits package.

Closing Date: 3rd January 2020

To apply, please send your CV and a cover letter quoting the job reference: SD/1119 to

For information on Astex Pharmaceuticals please visit:
and for information on Otsuka Pharmaceuticals please visit:


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Scientific Software Developer