Max Delbrück Center for Molecular Medicine (MDC)

Research Scientist for Start-Up Project

Max Delbrück Center for Molecular Medicine (MDC)

Berlin, Germany

The MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE (MDC) is a member of the Helmholtz Association of National Research Centers, supported by the Federal Government of Germany and the Land Berlin. We are seeking an exceptional research scientist for our academia-stage start-up project “Captain T Cell”.

Research Scientist
for Start-Up Project

About us:

At the academia-stage start-up project “Captain T Cell” we are developing ground-breaking T cell immunotherapies for cancer patients. The project is currently publicly funded by the GO-Bio grant of the BMBF and hosted by the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC). The MDC is located in the vibrant city of Berlin, Germany, and is one of the most important centers for biomedical research in the world. Applicants can find more information at https://go-bio.de/en/t-cell-immunotherapy-fight-blood-cancers.

Job description:

• Research: complex T cell culture assays, flow cytometry, cell separation and sorting, T cell engineering, in vitro and in vivo TCR characterization experiments, molecular biology, NGS, bioinformatics
• Translation and manufacturing: pre-clinical process development (wet lab and documentation) to manufacture engineered T cell products, establishment of partnerships with CDMOs
• Project management: regulatory-compliant documentation, creation of patent applications, goal-oriented project planning and management, internal and external presentation of research results

Profile:

• You are a reliable and well-structured person who wants to unfold his/her full potential and enthusiasm in a friendly and team-oriented start-up environment.
• You have a PhD, MD or equivalent qualification in a biomedical discipline.
• You bring hands-on experience with primary T cell cultures and cancer cell lines, flow cytometry, cell sorting, ELISA, immunological in vitro and in vivo assays, transient and stable gene engineering methods, murine tumor models, and molecular biology/cloning.
• Knowledge of adoptive T cell therapies, T cell receptor gene sequences, tumor antigens, HLAs and next generation TCR sequencing is necessary.
• Experience with the bioinformatic analysis of TCR gene sequences is a plus.
• Work experience regarding pre-clinical experiments of engineered T cells, process development for GMP manufacturing of ATMPs and planning and implementation of clinical studies are a plus.
• You have excellent oral and written communication skills in English. German skills are beneficial.

Details:

We are seeking a full-time employee to start at the earliest time point possible. Initially, the position will be limited until the end of 2020. Salary will be according to the German Federal salary scheme (TVÖD13).

Perspective:

Apply your entire scientific and personal skill set to shape the development of innovative immunotherapy products for end-stage cancer patients. Learn about translation and early product development at the interface of academic research and industry in a fast-growing field. Join our enthusiastic team and help us move the “Captain T Cell” project from the academic setting to a start-up company. We provide you with the opportunity to learn, grow and take on new challenges as we make this transition. After the end of the funding period and founding of our company, employment in the new company “Captain T Cell” is a possibility.

Comment:

The MDC is an equal opportunity employer and supports gender equality.

For further information please contact:

Dr. Janna Hachmann (janna.hachmann@mdc-berlin.de, phone +49 30 9406 3548)

Please, send your application including all documents (a short one-page cover letter (motivation, how your set of skills can provide value for the project), a CV (max. 2 pages) and the contact details of two referees) indicating the registration number 11123/2019 until 30th August 2019 preferably by e-mail in a single pdf file (max. 5 MB) as we do not return any documents to:

MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE
Personnel Department • POB 74 02 38 • 13092 Berlin
jobs@mdc-berlin.dewww.mdc-berlin.de

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Position

Research Scientist for Start-Up Project