The Children's Hospital of Philadelphia (CHOP)

Research Post Doctoral Fellow- Hematopoietic Stem Cell Biology and Gene Therapy

Children’s Hospital of Philadelphia Research Institute

Philadelphia, PA, United States

Job Summary

The Children’s Hospital of Philadelphia Research Institute is an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children, and is part of The Children’s Hospital of Philadelphia and University of Pennsylvania research community.

A Postdoctoral position in Hematopoietic Stem Cell Biology and Gene Therapy is available in the laboratory of Dr. Peter Kurre ., at the Children’s Hospital of Philadelphia Research Institute/ University of Pennsylvania. The Laboratory has longstanding expertise in hematopoietic stem cell biology and has actively investigated stem cell losses in Fanconi Anemia (FA) for over a decade. Ongoing work is focused on mechanisms underlying fetal stem cell losses in FA and their contribution to stem cell exhaustion and leukemogenesis that are a hallmark of FA. Investigations will involve a wide range of methods in stem cell and molecular biology, imaging and bioinformatics. The postdoctoral fellow will lead a specific research project investigating HSC biology and gene therapy approaches to hematopoietic rescue in FA.

The successful candidate will be highly self-motivated and creative. Excellent verbal and written communication skills are critical. Scrupulous attention to detail, excellent record keeping, and the ability to work independently in an expanding dynamic workgroup are essential. Candidates must have a recent degree in the biological sciences. Experience with mammalian cell culture, basic molecular and cell biology techniques are requirements, flow-cytometry, and mouse models are desirable. Experience with bioinformatic analysis of large datasets is strongly preferred. The applicant will have an opportunity to compete for trainee funding as part of their own career development.

Please send resume with cover letter to:

Olivia Cashan


Children’s Hospital of Philadelphia I Division of Hematology

Job Responsibilities

The successful candidate will thrive in a multi-disciplinary, collaborative team to extend, refine and enhance skills necessary for professional and career development, and broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. Postdocs will participate in project planning, recording and interpretation/evaluation of data, and communication of results. The candidate will acquire critical technical and lab management skills for their own career, and to become proficient at manuscript/grant writing. The successful candidate will participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also will participate in the supervision of junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Postdoctoral fellows at The Children’s Hospital of Philadelphia receive mentored training in a premier scientific and collaborative environment that includes extensive resources of the adjacent University of Pennsylvania. To learn more about the CHOP Research Institute and the research programs visit:

Required Licenses, Certifications, Registrations

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

Job Responsibilities

  1. Conduct independent scholarly research and develop new methods and protocols Participate in project planning, recording and evaluation of data Acquire technical, lab management and grant writing skills Participate in seminars, lectures, poster sessions and presentation at national meetings Supervise junior lab members Assist with other research projects

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children’s Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children’s Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products.

Children’s Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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